Latest Immune tolerance Stories
Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking the body’s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.
At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually pose no risk to health (self-antigens).
Imagine a single drug that would treat most, if not all, autoimmune disorders, such as asthma, inflammatory bowel disease, and Lupus.
Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body's own tissues.
It is no easy task to preserve the delicate balance that allows us to maintain a strong immune system that can defend us from harmful pathogens, but that is sensitive enough to correctly identify and spare our own cells.
The concept of pregnancy makes no senseâ€”at least not from an immunological point of view.
--However, Animal Study Also Points Toward Strategies for Success-- PHILADELPHIA, Aug.
Pediatric researchers have resolved an apparent contradiction in the field of prenatal cell transplantationâ€” a medical approach that holds future promise in correcting sickle cell disease and other serious congenital blood disorders.
The immune system's T-cells react to foreign protein fragments and therefore are crucial to combating viruses and bacteria. Errant cells that attack the body's own material are in most cases driven to cell death. Some of these autoreactive T-cells, however, undergo a kind of reeducation to become "regulatory T-cells" that keep other autoreactive T-cells under control.
- A trick or prank.