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Latest Immunohistochemistry Stories

2008-02-13 03:00:14

By Deavers, Michael T Although most diagnoses in gynecologic pathology are established through the examination of routine hematoxylin eosin-stained slides, immunohistochemical studies can be of assistance in some cases. The following case studies are used to illustrate the value of some relatively new markers in the diagnosis of gynecologic neoplasms and to highlight potential diagnostic pitfalls. (Arch Pathol Lab Med. 2008;132:175-180) CASE 1 Case History The patient is a 59-year-old...

2008-01-16 03:00:13

By Yip, Stephen Iafrate, A John; Louis, David N Abstract Advances in understanding the molecular underpinnings of cancer and in molecular diagnostic technologies have changed the clinical practice of oncologic pathology. The development of targeted therapies against specific molecular alterations in cancer further portends changes in the role of the pathology laboratory to guide such custom therapies. To reconcile the flood of scientific discoveries in this area, the promises of highly...

2007-12-22 06:00:33

By Frattini, Jared C Sosa, Julie Ann; Carmack, Susanne; Robert, Marie E * Data from the nuclear reactor explosion in Chernobyl and the atomic bomb detonations in Hiroshima and Nagasaki demonstrated an association between ionizing radiation and tumoriogenesis. There is a significant association between external beam radiation and radiation-induced sarcoma. Sclerosing epithelioid fibrosarcoma is a rare form of malignant fibrosarcoma that is low grade and indolent with distinct...

2007-08-16 06:16:45

By Liu, Lina Qian, Junqi; Singh, Harpreet; Meiers, Isabelle; Et al Context.-The separation of chromophobe renal cell carcinoma, oncocytoma, and clear cell renal cell carcinoma using light microscopy remains problematic in some cases. Objective.-To determine a practical immunohistochemical panel for the differential diagnosis of chromophobe carcinoma. Design.-Vimentin, glutathione S-transferase alpha (GST-alpha), CD10, CD117, cytokeratin (CK) 7, and epithelial cell adhesion molecule...

2007-02-14 09:00:00

By Takei, Hidehiro; Bhattacharjee, Meenakshi B; Rivera, Andreana; Dancer, Yeongju; Powell, Suzanne Z * Context.-Immunohistochemistry (IHC) has become an important tool in the diagnosis of brain tumors. Objective.-To review the latest advances in IHC in the diagnostic neuro-oncologic pathology. Data Sources.-Original research and review articles and the authors' personal experiences. Data Synthesis.-We review the features of new, useful or potentially applicable marker antibodies as well...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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