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Latest Immunotransplant Stories

2013-07-11 16:28:34

Cancer vaccines prime the immune system to attack cancer cells, decreasing tumor progression. IL-12p70, a molecule produced by certain types of immune cells, has been shown to reduce tumor progression, but delivering it as part of a cancer vaccine has been limited because of its toxicity in high doses. In the current issue of the Journal of Clinical Investigation, Dr. Beatriz Carreno and colleagues at Washington University report the results of a clinical trial that tested a vaccine to treat...

2012-03-06 06:21:30

(Ivanhoe Newswire)-- Those suffering from Melanoma may have new hope. A recent study shows that a patient's own cells may reduce advanced melanoma and send the cancer into remission. Cassian Yee, M.D., a member of the Clinical Research Division of Fred Hutchinson Cancer Research Center, had a goal to find the ideal cellular environment in which to infuse 15 billion to 20 billion cancer-fighting CD8+ T cells so that they remain for as long as possible in the body to battle the tumors. The...

2011-04-28 00:15:44

Like brainy bookworms unprepared for the rough and tumble of post-graduation life, white blood cells trained by scientists to attack tumors tend to fade away quickly when injected into cancer patients. Dana-Farber Cancer Institute scientists, however, have developed a technique that can cause such cells to survive in patients' bloodstreams for well over a year, in some cases, without the need of other, highly toxic treatments, a new study shows. In a paper published in the Apr. 27 issue of...

2010-12-14 06:00:00

CAMBRIDGE, Mass., Dec. 14, 2010 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company developing novel therapies to treat autoimmune diseases and cancer by modulating T cell activity, today announced that it has initiated a Phase 1 clinical trial to assess the safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of TRX518, a monoclonal antibody designed to enhance the immune system by enabling T cells to more effectively attack cancer cells. The Phase 1 trial will...

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2010-11-26 07:55:18

Dendritic cell vaccine induces immune responses in patients A new process for creating a personalized vaccine may become a crucial tool in helping patients with colorectal cancer develop an immune response against their own tumors. This dendritic cell (DC) vaccine, developed at Dartmouth and described in a research paper published this week in the journal Clinical Cancer Research, was used after surgical resection of metastatic tumors to try to prevent the growth of additional metastases....

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2010-04-07 06:51:59

Rush University Medical Center leads nationwide study Rush University Medical Center is leading a nationwide Phase III clinical trial to determine whether a promising vaccine for advanced melanoma can effectively treat the deadly skin cancer. An earlier Phase II trial of the experimental drug involving 50 patients with metastatic melanoma had stunning results. Eight patients recovered completely and four partially responded to the vaccine. "Very few treatment options exist for patients with...

2008-07-21 18:00:46

Plants could act as safe, speedy factories for growing antibodies for personalized treatments against a common form of cancer, according to new findings from the Stanford University School of Medicine. The findings came in the first human tests of an injectable vaccine grown in genetically engineered plants. The treatments, which would vaccinate cancer patients against their malignant cells, could lead to earlier personalized therapy to tackle follicular B-cell lymphoma, an immune-system...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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