Latest Inbred strain Stories
Researchers including Jackson Laboratory Professor Gary Churchill, Ph.D., have found a single nucleotide polymorphism (SNP) difference in cocaine and methamphetamine response between two substrains of the C57BL/6 or "Black 6" inbred laboratory mouse, pointing to Cyfip2 as a regulator of cocaine response with a possible role in addiction.
With a 95 percent genomic similarity to humans, mice have long been used to learn about the genetic causes of human disease.
The Collaborative Cross (CC) represents a large collection of new inbred mouse strains created by the mouse genetics community aimed at revolutionizing the study of complex genetic traits and diseases.
Sharing about 95 percent of their genes with humans, mice are recognized around the world as the leading experimental model for studying human biology and disease.
Inbred male sperm have been found to fertilize fewer eggs when in competition with non-inbred males according to a new study by the University of East Anglia.