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2013-06-06 18:27:15

Genetic mutation of a testis stem cell actually gives the disease an edge, making older fathers more likely to pass it along to their children Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan Syndrome are so common: a mutation that causes the disease disproportionately increases a normal father´s production of sperm carrying the disease trait. When this Noonan syndrome mutation arises in a normal sperm stem cell it makes that cell more...

2008-09-08 12:00:11

By Courts, Cornelius Montesinos-Rongen, Manuel; Brunn, Anna; Bug, Stefanie; Siemer, Dorte; Hans, Volkmar; Blumcke, Ingmar; Klapper, Wolfram; Schaller, Carlo; Wiestler, Otmar D; Kuppers, Ralf; Siebert, Reiner; Deckert, Martina Abstract Primary lymphomas of the CNS (PCNSLs) show molecular features of the late germinal center exit B-cell phenotype and are impaired in their terminal differentiation as indicated by a lack of immunoglobulin class switching. Because the positive regulatory domain...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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