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Latest Indiana University School of Medicine Stories

2011-06-06 15:38:20

Researchers at the Indiana University School of Medicine have discovered a peptide that short circuits a pathway for chronic pain. Unlike current treatments this peptide does not exhibit deleterious side effects such as reduced motor coordination, memory loss, or depression, according to an article in Nature Medicine posted online June 5, 2011. The peptide, CBD3, has been shown in mice to interfere with signals that navigate calcium channels to produce pain. Unlike other substances that block...

2011-05-26 15:29:39

Omega 3 fatty acids may be beneficial for more than just the heart. Research at the Indiana University School of Medicine disclosed at a molecular level a potential therapeutic benefit between these dietary supplements, alcohol abuse and psychiatric disorders. In a multi-year study, researchers showed conclusive behavioral and molecular benefits for omega 3 fatty acid given to mice models of bipolar disorder. The fatty acid DHA, which is one of the main active ingredients in fish oil,...

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2011-05-24 13:39:15

The lists of potential side effects that accompany prescription drugs have ballooned in size, averaging 70 reactions per drug, a number that can overwhelm physicians trying to select suitable treatments for their patients, according to a new study of drug labels. Long lists of drug side effects"”whether found in magazine advertisements or in package inserts"”are a familiar sight to patients and doctors. Now researchers from the Regenstrief Institute and the Indiana University...

2011-05-23 22:16:45

A group of proteins that act as the body's built-in line of defense against invading bacteria use a molecular trick to induce bacteria to destroy themselves, researchers at the Indiana University School of Medicine have determined. The research could point the way toward new anti-bacterial treatments that could take on bacteria that are resistant to antibiotics. The proteins, called Peptidoglycan Recognition Proteins (PGRPs), are able to detect and target bacteria because bacteria are unique...

2011-05-16 20:00:46

An international research team has identified a lung protein that appears to play a key role in smoking-related emphysema and have crafted an antibody to block its activity, Indiana University scientists reported. The research, conducted in mice, suggests that the protein, a cytokine named EMAPII, could provide a target for drugs to treat emphysema, said Irina Petrache, M.D., associate professor of medicine at the Indiana University School of Medicine. The research was posted online May 16...

2011-03-24 20:17:18

An orphan drug originally used for HIV treatment has been found to short-circuit the process that results in additional sensitivity and pain from opioid use. The study by researchers at the Indiana University School of Medicine is reported in the March 25, 2011 issue of Brain, Behavior and Immunity. The researchers say the finding in animal models may ultimately make morphine a safer and more effective drug. Traditionally opioids were used to relieve pain following surgery, from cancer and at...

2011-02-10 14:59:22

An innovative model of dementia care developed by researchers at the Indiana University School of Medicine and the Regenstrief Institute significantly reduces emergency department visits and hospitalizations, and encourages use of medications that are not harmful to older brains. The result is improved health for older adults and their family caregivers and lower healthcare costs, according to a paper evaluating the model in real world use. The paper appears in Volume 15, Issue 1, 2011 of the...

2011-01-30 10:50:01

An antibiotic known for its immunosuppressive functions could also point the way to the development of new anti-cancer agents, researchers at the Indiana University School of Medicine have reported.The study determined that the compound, tautomycetin, targets an enzyme called SHP2, which plays an important role in cell activities such as proliferation and differentiation. Interestingly, SHP2 mutations are also known to cause several types of leukemia and solid tumors. The findings were...

2011-01-24 17:00:33

A new study from the Indiana University School of Medicine and the Regenstrief Institute has found that Black and especially Hispanic young women are screened for chlamydia at a significantly higher rate than young white women. This discrepancy in screening rates may contribute to nationwide reporting of higher rates of this sexually transmitted disease among minority young women. The research, which used data from more than 40,000 visits to health care facilities, appears in the February...

2011-01-06 13:59:49

A simpler form of testing individuals with risk factors for diabetes could improve diabetes prevention efforts by substantially increasing the number of individuals who complete testing and learn whether or not they are likely to develop diabetes. Approximately 60 million Americans, one-third of the adult population, are pre-diabetic. Thirty percent of these individuals will develop Type 2 diabetes in less than a decade, yet most don't know they are at high risk for the disease. A study...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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