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Latest Indole Stories

2014-04-03 12:19:54

Bacteria "plan ahead" by tightening their belts to help them survive looming lean periods, researchers at Cambridge have discovered. At a time when there is growing concern about rising antibiotic resistance, the results – published in the journal PLOS ONE – could lead to new ways of combatting dangerous bacteria. For many years, people thought bacteria worked by simply consuming resources until they ran out, and then entering a stationary, non-growing, phase. Working with physicists...

2011-10-24 22:48:47

Biologists at the University of California, San Diego have succeeded in unraveling, for the first time, the complete chain of biochemical reactions that controls the synthesis of auxin, the hormone that regulates nearly all aspects of plant growth and development. Their discovery, detailed in a paper in this week's online edition of the Proceedings of the National Academy of Sciences, will allow agricultural scientists to develop new ways to enhance or manipulate auxin production to...

2010-09-01 20:52:46

Research reveals bacterial altruism makes populations stronger than individuals Drug resistant bacteria are a problem in many environments, especially healthcare institutions. While the ways in which these cells become resistant are understood at the cellular level, until now, the bacteria's survival strategies at the population level remained unclear. A new study by James Collins and colleagues at Boston University and the Wyss Institute for Biologically Inspired Engineering at Harvard...

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2009-08-17 09:45:00

In an advance toward the first portable device for detecting human bodies buried in disasters and at crime scenes, scientists today report early results from a project to establish the chemical fingerprint of death. Speaking here at the 238th National Meeting of the American Chemical Society (ACS), they said a profile of the chemicals released from decomposing bodies could also lead to a valuable new addition to the forensic toolkit: An electronic device that could determine the time elapsed...

2008-12-15 09:52:36

An anti-cancer compound found in broccoli and cabbage works by blocking a key enzyme associated with rapidly advancing cancer. The compound found in the veggies, indole-3-carbinol, is already in human clinical trials because of its ability to stop breast and prostate cancer growth in mice. The new findings are the first to explain how indole-3-carbinol stops cell growth. Researchers at the University of California, Berkeley, showed that indole-3-carbinol inhibits the enzyme elastase. Elastase...

2008-09-22 09:00:59

SRI International, an independent nonprofit research and development organization, announced today it has been awarded a contract to develop broad-spectrum antibiotics from the Defense Threat Reduction Agency (DTRA), an agency within the United States Department of Defense (DoD). The new three-year, $8.3 million contract will enable preclinical research in developing drugs against a broad range of bioterror agents including anthrax, plague and tularemia. "We are excited and pleased to be...

2008-08-26 03:00:17

By Pratchayasakul, Wasana Pongchaidecha, Anchalee; Chattipakorn, Nipon; Chattipakorn, Siriporn Tabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T. divaricata as well as its potential therapeutic benefits especially of the alkaloidal and non-...

2008-08-09 03:00:24

By Yang, Yue Xu, Richard; Ma, Choong-je; Vlot, A Corina; Klessig, Daniel F; Pichersky, Eran The plant hormone auxin (indole-3-acetic acid [IAA]) is found both free and conjugated to a variety of carbohydrates, amino acids, and peptides. We have recently shown that IAA could be converted to its methyl ester (MeIAA) by the Arabidopsis (Arabidopsis thaliana) enzyme IAA carboxyl methyltransferase 1. However, the presence and function of MeIAA in vivo remains unclear. Recently, it has been shown...

2008-05-16 06:00:00

By Ward, Weslyn C Lamb, Erin C; Gooden, David; Chen, Xin; Burinsky, David J; Simon, John D ABSTRACT Three naturally occurring pyrrole acids were found in Sepia, human black hair, and bovine choroid and iris melanosomes using high-performance liquid chromatography and mass spectrometry- pyrrole-2,3-dicarboxylic acid (PDCA), pyrrole-2,3,5-tricarboxylic acid (PTCA) and pyrrole-2,3,4,5-tetracarboxylic acid (PTeCA). PDCA and PTCA are common markers quantified from oxidative degradation of...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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