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Latest Indoles Stories

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2010-09-07 12:24:56

U.S. researchers said Monday that magic mushrooms may help ease the anxiety that accompanies late-stage cancer. They said that cancer patients given a moderate dose of the hallucinogen psilocybin were measurably less depressed six months after a single dose compared with a placebo. The study of 12 cancer patients was designed to prove that hallucinogenic drugs could be studied as a way to relieve the distress of advanced cancer. The study, which was published in the Archives of General...

2010-08-02 07:00:00

SCHAUMBURG, Ill., Aug. 2 /PRNewswire/ -- Sagent Pharmaceuticals, Inc., a privately-held specialty pharmaceutical company, today announced two FDA approvals -- sumatriptan succinate injection and rocuronium bromide injection. Sumatriptan succinate injection (sumatriptan) will be available in 6 mg per 0.5 mL latex-free vials. Rocuronium bromide injection will be available in latex-free vials of 50 mg per 5 mL and 100 mg per 10 mL. According to 2009 IMS data, the U.S. market for injectable...

2009-11-18 14:40:39

Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding. To mitigate NSAIDs' adverse effects on the stomach, misoprostol, a non-selective prostaglandin E1 (PGE1) analogue, has been prescribed as the first choice for prevention of NSAID-induced injuries, but often induces severe adverse effects. There remain unmet medical needs for drugs with...

2009-08-10 07:00:00

MARKHAM, ON, Aug. 10 /PRNewswire-FirstCall/ - AlphaRx Inc. (OTC BB:ALRX.OB - News), an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to announce that it has been granted a comprehensive patent in China for its topical platform technology entitled "Vehicle For Topical Delivery of Anti-Inflammatory Compounds." The platform is an integral part of the Company's clinical stage product candidate Indaflex(TM)....

2008-12-15 09:52:36

An anti-cancer compound found in broccoli and cabbage works by blocking a key enzyme associated with rapidly advancing cancer. The compound found in the veggies, indole-3-carbinol, is already in human clinical trials because of its ability to stop breast and prostate cancer growth in mice. The new findings are the first to explain how indole-3-carbinol stops cell growth. Researchers at the University of California, Berkeley, showed that indole-3-carbinol inhibits the enzyme elastase. Elastase...

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2008-12-03 15:35:00

An anti-cancer compound found in broccoli and cabbage works by lowering the activity of an enzyme associated with rapidly advancing breast cancer, according to a University of California, Berkeley, study appearing this week in the online early edition of the journal Proceedings of the National Academy of Sciences.The compound, indole-3-carbinol, is already undergoing clinical trials in humans because it was found to stop the growth of breast and prostate cancer cells in mice.The new findings...

2008-10-01 06:00:48

Research and Markets (http://www.researchandmarkets.com/research/370328/inhaled_cns_therap) has announced the addition of the "Inhaled CNS Therapeutics - Markets & Opportunities" report to their offering. Delivering drugs to the central nervous system presents unique challenges. But, drug developers and researchers have discovered that delivering CNS therapeutic drugs via inhalation mitigates several of these issues. The accessibility and vascular structure of the nose make it an...

2008-09-24 15:00:46

By WINDER, Virginia This article was written by a contributor. It is not to be reproduced without permission from the Taranaki Daily News and charges may be incurred. ---------------------------------------------- A FAILED quest to make a healthy beer has led a former winemaker to water. But not just any water. Auckland woman Dee Babich has invented Sero2, a sparkling mineral water from Whakatane with a twist. The twist is an essential amino acid, called L-tryptophan, derived from...

2008-08-09 03:00:24

By Yang, Yue Xu, Richard; Ma, Choong-je; Vlot, A Corina; Klessig, Daniel F; Pichersky, Eran The plant hormone auxin (indole-3-acetic acid [IAA]) is found both free and conjugated to a variety of carbohydrates, amino acids, and peptides. We have recently shown that IAA could be converted to its methyl ester (MeIAA) by the Arabidopsis (Arabidopsis thaliana) enzyme IAA carboxyl methyltransferase 1. However, the presence and function of MeIAA in vivo remains unclear. Recently, it has been shown...

2008-07-01 09:01:11

NuPathe has reported positive Phase I results for NP101, a novel drug-device patch for acute migraine in clinical development. NuPathe's NP101 combines its SmartRelief proprietary iontophoretic transdermal technology with sumatriptan, the most widely prescribed treatment for acute migraine in the US and the active ingredient in Imitrex. The study was a Phase I, single center, single-dose, open label, five-way crossover study to compare the pharmacokinetics of two NP101 patch formulations...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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