Latest Induced pluripotent stem cell Stories
While it was once believed that every cell in a person’s body contains the same DNA code, new research led by experts at the Salk Institute has found an unexpected level of variation among the genomes of different neurons originating from the same person’s brain.
For the first time, scientists have taken stem cells from chimpanzees and bonobos and turned them into induced pluripotent stem cells (iPSCs), and their work has helped to highlight some of the differences between humans and great apes.
In a feat of modern-day alchemy with huge potential for regenerative medicine, Stanford University School of Medicine scientists have developed a fast, efficient way to turn cells extracted from routine liposuction into liver cells.
Bioengineers at the University of California, Berkeley, have shown that physical cues can replace certain chemicals when nudging mature cells back to a pluripotent stage, capable of becoming any cell type in the body.
A research team led by Professor Noriyuki Tsumaki of the Center for iPS Cell Research and Application (CiRA) at Kyoto University and Dr. Hidetatsu Ohtani, a former CiRA member who now works as a post doctoral fellow at Osaka University Graduate School of Medicine, has succeeded in directly converting human dermal fibroblasts into induced chondrogenic cells (iChon cells) without passing through an iPS cell stage in a process known as direct reprogramming.
Researchers have discovered how the most common genetic abnormality in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) kills neurons and have successfully developed a therapeutic strategy to block this neurodegeneration in neurons made from the skin cells of ALS patients.
Researchers have discovered a new, highly efficient way to produce neural stem cells from human pluripotent stem cells that can then go on to form neurons in the brain.