Latest Inflammatory bowel disease Stories
SAN DIEGO, July 31, 2012 /PRNewswire/ -- Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced today the market launch of its proprietary new generation monitoring test, PROMETHEUS Anser IFX. This test measures drug (infliximab) and drug antibody levels in one sample among inflammatory bowel disease (IBD) patients using infliximab - helping physicians identify potential causes for loss of treatment response and helping to guide patient...
HORSHAM, Pa. and LEIDEN, Netherlands, July 16, 2012 /PRNewswire/ -- Janssen Biotech, Inc. and Janssen Biologics B.V. announced today the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) and a Type II Variation to the European Medicines Agency (EMA) requesting approval of SIMPONI® (golimumab) for the treatment of adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response...
A naturally occurring protein called TLR1 plays a critical role in protecting the body from illnesses caused by eating undercooked pork or drinking contaminated water, according to new research from the University of Southern California (USC). The discovery may help create more effective oral vaccines for infections of the respiratory and gastrointestinal systems and already has launched an examination of how TLR1 is linked to inflammatory bowel disease, says R. William DePaolo, assistant...
NUTLEY, N.J., July 1, 2012 /PRNewswire/ -- A jury in New Jersey late Friday returned an $18 million verdict to two former Accutane users against Nutley, N.J.-based pharmaceutical companies Hoffmann La-Roche Inc. and Roche Laboratories, subsidiaries of Roche Holding AG (ROG). The plaintiffs, Katie Rossitto and Riley Wilkinson, took Accutane for treatment of their acne in the 1990s and developed ulcerative colitis--a debilitating, permanent disease--as a result. Each was awarded $9...
HORSHAM, Pa., June 25, 2012 /PRNewswire/ -- In advance of releasing his debut album, musician and American Idol alumnus Casey Abrams has created an original song entitled "Chip on Your Shoulder" and music video inspired by his personal experience with inflammatory bowel disease (IBD) and the people he met through the national disease awareness campaign IBD Icons. Starting today, people can view Abrams' music video by joining the fan club at www.IBDIcons.com. For every fan who...
Mice carrying a set of friendly microbes that are usually found in humans fail to develop a proper immune system and are left susceptible to illness as a result. The findings in the June 22nd issue of the journal Cell, a Cell Press publication, show that animals have coevolved with and rely on their own very special array of microbial partners. As far as our immune systems are concerned, not just any bug collection will do. "Human microbe-colonized mice have gut immune systems that look...
Researchers at Baylor College of Medicine and Texas Children's Hospital have identified commensal bacteria in the human intestine that produce a neurotransmitter that may play a role in preventing or treating inflammatory bowel diseases such as Crohn's disease. "We identified, to our knowledge, the first bifidobacterial strain, Bifidobacterium dentium, that is capable of secreting large amounts of gamma-aminobutyric acid (GABA). This molecule is a major inhibitory neurotransmitter in the...
Study published in Science indicates that fungus plays a role in inflammatory bowel disease Cedars-Sinai researchers say their examination of the fungi in the intestines suggests an important link between these microbes and inflammatory diseases such as ulcerative colitis. In the new study, published in the June 8 issue of Science, researchers at Cedars-Sinai's Inflammatory Bowel and Immunobiology Research Institute identified and characterized the large community of fungi inhabiting...
Good microbes that promote normal health can 'turn bad' if found outside the intestine The healthy human intestine is colonized with over 100 trillion beneficial, or commensal, bacteria of many different species. In healthy people, these bacteria are limited to the intestinal tissues and have a number of helpful properties, including aiding in the digestion of food and promoting a healthy immune system. However, when it comes to commensal bacteria, location is key. While commensal...
According to court documents, on April 10th 2012, a Georgia man, Nelson Eddie Caviness, filed a lawsuit in Georgia Northern District Court (case no. 1:2012cv01209) alleging he suffered inflammatory bowel disease from Accutane. Accutane (isotretinoin), manufactured by Hoffman-LaRoche, Inc., is a popular acne medication introduced in 1982. On April 26th, 2012, Caviness’s case was transferred to the Accutane Multidistrict Litigation (MDL 1626) in the U.S. District Court, Middle District of...
