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Last updated on April 16, 2014 at 17:34 EDT

Latest inflammatory response Stories

2013-03-05 12:29:35

HOUSTON, March 5, 2013 /PRNewswire-USNewswire/ -- The inflammation of fat tissue is part of a spiraling series of events that leads to the development of type 2 diabetes in some obese people. But researchers have not understood what triggers the inflammation, or why. In Cell Metabolism this month (cover), scientists from The Methodist Hospital report fat cells themselves are at least partly to blame -- high calorie diets cause the cells to make major histocompatibility complex II, a group of...

2012-07-31 02:27:15

SEATTLE, July 31, 2012 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today reported that it believes it has identified the proteins that activate the alternative pathway of the complement system, an important part of the immune system. The work was led by the Company's collaborator, Professor Wilhelm Schwaeble of the University of Leicester, and Omeros controls the worldwide exclusive rights to this discovery. The complement system plays an important role in the inflammatory response and...

2012-05-24 22:00:51

Acute inflammatory diseases, such as sepsis, as well as chronic inflammatory diseases like diabetes and arthritis, develop as a result of sustained inflammation of the blood vessel wall. Researchers at Brigham and Women's Hospital (BWH) have discovered that a microRNA (small, non-coding RNA molecule) called miR-181b can reduce the inflammatory response that is responsible for such diseases. The findings, by researchers led by Mark Feinberg, MD from BWH and Harvard Medical School, will pave...

2012-05-14 20:22:03

A small, external bioreactor holding human cells pumped out an anti-inflammatory protein to prevent organ damage and other complications in a rat with acute inflammation caused by bacterial products in a model of sepsis, according to a report from researchers at the University of Pittsburgh School of Medicine and the McGowan Institute for Regenerative Medicine. The findings were published today in the inaugural issue of Disruptive Science and Technology. Inflammation is a necessary...

2012-04-23 22:18:31

Researchers interested in determining the direct effects of a high saturated fat and high cholesterol (HFHC) diet on implanted fetal hippocampal tissues have found that in middle-aged laboratory rats the HFHC diet elevated microglial activation and reduced neuronal development. While the resulting damage was due to an inflammatory response in the central nervous system, they found that the effects of the HFHC diet were alleviated by the interleukin (IL)-1 receptor antagonist IL-1Ra, leading...

Yes, Stress Can Make You Sick. But How?
2012-04-03 07:47:02

Researchers, led by Sheldon Cohen, at Carnegie Mellon University have discovered that psychological stress increases risk for depression, heart disease and infectious diseases. And now they know how. The researchers found that psychological stress causes the body to lose its ability to regulate the inflammatory response. According to Cohen, “Inflammation is partly regulated by the hormone cortisol and when cortisol is not allowed to serve this function, inflammation can get out of...

2012-04-02 10:25:10

PITTSBURGH, April 2, 2012 /PRNewswire/ -- Stress wreaks havoc on the mind and body. For example, psychological stress is associated with greater risk for depression, heart disease and infectious diseases. But, until now, it has not been clear exactly how stress influences disease and health. (Logo: http://photos.prnewswire.com/prnh/20020422/CMULOGO) A research team led by Carnegie Mellon University's Sheldon Cohen has found that chronic psychological stress is associated with the body...

2011-10-05 21:57:57

Potential therapeutic target for treating disorders like age-related macular degeneration Conditions like atherosclerosis and age-related macular degeneration (AMD) -- the most common cause of blindness among the elderly in western societies -- are strongly linked to increased oxidative stress, the process in which proteins, lipids and DNA damaged by oxygen free radicals and related cellular waste accumulate, prompting an inflammatory response from the body's innate immune system that...

2011-04-18 14:47:33

Loyola study finds a patient's binge drinking may mislead doctors about a blood test used in timing an operation A Loyola University Health System study has found another reason to not binge drink alcohol. Binge drinking, researchers found, could change the body's immune system response to bone injuries. "This tremendously complicates the trauma care of these patients," said bone biologist John Callaci, PhD, senior author of the study. The study, which was based on a rodent model, is being...

2010-10-08 02:09:20

A study has detected a correlation between childhood adversity and exaggerated inflammatory response to stress among seemingly healthy people. It may shed light on risk for depression, other illnesses later in life. Seemingly healthy adults, if they were abused or neglected during childhood, may suffer physiological consequences decades later. In research published online last week by the journal Neuropsychopharmacology,  a team led by psychiatrists at Brown University and Butler...