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Last updated on April 17, 2014 at 14:51 EDT

Latest Inhibitory postsynaptic potential Stories

2009-04-02 12:11:28

University of California, Berkeley, graduate student Alistair Boettiger has amassed a beautiful collection of seashells, but not by combing the beach. He created them in his computer.He and George Oster, a UC Berkeley biophysicist, along with University of Pittsburgh mathematical neuroscientist Bard Ermentrout, have written a computer program that generates the complex patterns of seashells using simple principles developed to explain how the brain works and how memories are stored.The...

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2009-02-26 09:07:00

New research reveals a sophisticated brain mechanism that is critical for filtering out irrelevant signals during demanding cognitive tasks. The study, published by Cell Press in the February 26 issue of the journal Neuron, also provides some insight into how disruption of key inhibitory pathways may contribute to schizophrenia. "The ability to keep track of information and one's actions from moment to moment is necessary to accomplish even the simple tasks of everyday life," explains senior...

2007-04-26 12:12:15

A U.S. study has found morphine blocks the brain's ability to strengthen inhibitory synapse connections -- an important finding for addiction therapy. Brown University Professor Julie Kauer and colleagues found as little as a single dose of morphine could contribute to addiction. The study also supports a theory that addiction is a disease of learning and memory. In the study, the researchers found long-term potentiation, or LTP, is blocked in the brains of rats given as little as a...

2005-10-21 19:41:13

La Jolla, CA - Delving ever deeper into the intricate architecture of the brain, researchers at The Salk Institute have now described how two different types of nerve cells, called neurons, work together in tiny sub-networks to pass on just the right amount and the right kind of sensory information. Their study, published online by Nature Neuroscience, depicts how specific types of inhibitory neurons in the visual cortex of a rat brain are wired to, and "talk" with, discrete excitatory...

2005-08-26 19:44:59

New Haven, Conn. - Inhibitory systems are essential for controlling the pattern of activity in the cortex, which has important implications for the mechanisms of cortical operation, according to a Yale School of Medicine study in Neuron. The findings demonstrate the inhibitory network is central to controlling not only the amplitude, extent and duration of activation of recurrent excitatory cortical networks, but also the precise timing of action potentials, and, thus, network...

2005-08-23 13:41:40

Sacha Nelson of Brandeis University in Waltham, MA and Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA and their colleagues report online today in the Proceedings of the National Academy of Sciences Early Edition that spontaneous neuronal activity is reduced in the cortex of a knockout mouse model for the childhood neurodevelopmental disorder, Rett Syndrome. The Rett Syndrome Research Foundation (RSRF) and the McKnight Foundation funded this project. Rett...