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Last updated on April 17, 2014 at 8:20 EDT

Latest Inosine Stories

2013-12-26 12:21:02

Potential Neuroprotective Therapy Ready for Next Stage of Development after Michael J. Fox Foundation Funding NEW YORK, Dec. 26, 2013 /PRNewswire-USNewswire/ -- New findings published in JAMA Neurology from research into a potentially protective therapy for Parkinson's disease (PD) show that with medical supervision, urate levels may safely be raised while mitigating risk of complications such as gout. Previous research showed that higher levels of the antioxidant urate were...

2013-12-24 13:31:09

The drug inosine appears to be a safe and effective way to raise blood and cerebrospinal fluid urate levels in patients with early Parkinson disease (PD), suggesting it may be a potential strategy to slow the disability progression of the degenerative neurological disorder, according to a report published by JAMA Neurology, a JAMA Network publication. Urate is an end product of human metabolism. Animal experiments suggest that urate may protect against PD, and higher blood urate levels are...

2013-12-24 13:26:28

Phase 2 trial supports further investigation of urate's ability to slow disease progression A clinical trial assessing the potential of the nutritional supplement inosine to treat Parkinson disease has found that the studied dosages successfully raised participants' levels of the antioxidant urate without producing serious side effects. Results of the two-year phase 2 trial – conducted by a consortium led by investigators at Massachusetts General Hospital (MGH), Harvard School of Public...

2011-04-20 13:11:35

A combination therapy, including a compound already used by humans, restores skilled use of limb in rodent model After the acute treatment window closes, the only effective treatment for stroke is physical/occupational therapy. Now scientists from Children's Hospital Boston report a two-pronged molecular therapy that leads to significant recovery of skilled motor function in a rat model of stroke. Their findings are reported April 20 in the Journal of Neuroscience. By combining two molecular...

2010-06-03 05:45:00

BELGRADE, Serbia, June 3 /PRNewswire-FirstCall/ - Hard to Treat Diseases, Inc. (HTDS:PK), http://www.htdsmedical.com announced today that researchers from its Slavica BioChem (www.slavicabiochem.com) division in Belgrade made a great progress in the experimental findings to aid in the suppression or ultimately cure of Multiple Sclerosis which are comparable with investigations of other MS-Research groups around the world. In a recent press release posted on May 24, 2010 Abbott, and Biogen...

2008-09-11 00:00:10

A researcher at Florida State University says he's found a mechanism in proteins that helps explain evolution at molecular levels. Wei Yang said he and colleagues from FSU, Duke University and Brandeis University have produced models of the enzyme inosine monophosphate dehrydrogenase, which is responsible for initiating certain metabolic processes in DNA and RNA, the university said Wednesday in a news release. "In creating these simulations of IMPDH, we observed something that hadn't been...