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Latest Institute for Research in Biomedicine Stories

Method Invented To Reproduce Marine Substances Of Pharmacological Interest
2013-09-04 12:18:51

Institute for Research in Biomedicine / IRB Barcelona Chemists from the Institute of Research in Biomedicine (IRB) and from the R+D department of PharmaMar have devised a new synthesis method with pipecolidepsin A, a compound that is active against eleven types of cancers and property of PharmaMar. This advance opens the door to copying and improving 38 natural molecules derived from marine sponges that are very promising for the treatment of various diseases. In 2008 the Spanish...

2013-06-18 13:17:51

Researchers at IRB Barcelona and IBEC achieve photo-switchable molecules to control protein-protein interactions in a remote and non-invasive manner. These tools will serve as a prototype to develop photo-switchable drugs, whose effects would be limited to a given region and time, thus reducing the side effects on other regions. The article, cover and “Very Important Paper” of Angewandte Chemie, is a highlighted result of the European project “OpticalBullet”,...

2013-04-19 17:57:03

-This is the first study that studies and quantifies 1,600 known adverse effects of drugs currently on the market. -The scientists Miquel Duran and Patrick Aloy provide a description of the molecular processes responsible for more than 1,000 secondary effects. -This knowledge, which is available to the scientific community, may be of great use to minimize and predict adverse effects during drug design. Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory...

ALBA Synchrotron Used For First Time As A Microscope To Determine Protein Structure
2013-04-10 09:55:24

Universitat Autonoma de Barcelona The structure of the protein LC8 is linked to cell division and medical applications A team led by David Reverter, a researcher at the Institute of Biotechnology and Biomedicine (IBB) of the UAB, has determined for the first time the three-dimensional structure of a protein pair: LC8 and Nek9. Depending on whether or not they bind, Nek9 ensures that the chromosomes group and separate correctly during cell division. By analysing the 3D structure,...

Researchers Discover Mechanism That Regulates Steroid Hormone Production In Drosophila
2013-03-07 16:06:22

Institute for Research in Biomedicine (IRB Barcelona) Looking at the transformation of a fly larva into a pupa may help researchers to understand the molecular mechanisms that trigger puberty. A study conducted on the fruit fly, Drosophila melanogaster, by scientists at the Institute for Research in Biomedicine (IRB Barcelona) led by ICREA research professor Marco Milán, identifies an miRNA as key to the relationship between hormones that control growth and sexual maturity....

2012-11-30 11:55:59

The study, published in PNAS, opens the way for large-scale screenings to identify targets for cancer therapy. The wing of a fruit fly may hold the key to unraveling the genetic and molecular events that transform a normal cell into a cancerous one. The study, conducted on Drosophila melanogaster by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and led by ICREA researcher Marco Milán, has reproduced each of the steps known to take place when a...

Key Process Discovered That Allows Colon Cancer To Metastasize
2012-11-13 10:57:33

Institute for Research in Biomedicine (IRB Barcelona) The study, published in the prestigious journal Cancer Cell, reveals that tumor cells of the colon must form alliances with healthy cells in order to colonize other organs during metastasis A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability of colon cancer to metastasize lies in...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'karpos', fruit.
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