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Latest Institute of Cancer Research Stories

‘Barcode’ Blood Test Reads Genetic Results, Helps Detect Aggressive Prostate Cancer
2012-10-09 10:00:23

Lawrence LeBlond for redOrbit.com - Your Universe Online A blood test that can read genetic results much like a ℠barcode´ has been developed by scientists at the Institute of Cancer Research (ICR) and the Royal Marsden NHS Foundation. This genetic blood test can also detect the most aggressive prostate cancers by reading particular patterns of gene activity. Research staff believe the test could eventually be used to select patients who are most in need of immediate...

2012-09-14 15:20:21

A whole-genome scan to identify large-scale chromosomal damage can help doctors choose the best treatment option for children with neuroblastoma, one of the most common types of childhood cancer, finds an international collaboration jointly led by The Institute of Cancer Research, London. The researchers called for all children diagnosed with neuroblastoma worldwide to have a whole-genome scan as a standard part of their treatment. Neuroblastoma, a cancer of the developing nervous...

2012-07-11 14:47:35

A new drug combination could offer hope to children with neuroblastoma — one of the deadliest forms of childhood cancer — by boosting the effectiveness of a promising new gene-targeted treatment. Researchers at The Institute of Cancer Research in London have found a way to overcome the resistance of cancer cells to a drug called crizotinib, which recently showed positive early results in its first trial in children with cancer. Crizotinib has already been licensed by the US...

2012-05-21 05:26:29

(Ivanhoe Newswire) — Some say the number of cases is growing at an epidemic rate! In fact, melanoma is the fastest growing cancer in the U.S. Now, a new study shows the drug, dabrafenib, has been shown to have the most activity of any systematic treatment to date against secondary melanoma tumours in the brain. A phase 1 trial shows the new drug causes substantial shrinking of metastatic tumours in patients. Dabrafenib blocks the activity of the cancer-causing mutated form of the...

2012-05-10 23:00:47

The human body does a great job of generating new cells to replace dead ones but it is not perfect. Cells need to communicate with or signal to each other to decide when to generate new cells. Communication or signaling errors in cells lead to uncontrolled cell growth and are the basis of many cancers. At The University of Texas Health Science Center at Houston (UTHealth) Medical School, scientists have made a key discovery in cell signaling that is relevant to the fight against melanoma...

2012-03-29 02:27:15

Researchers identify genetic markers of drug sensitivity in cancer cells In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The team uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs. One of the key responses the team found was that cells from a childhood bone cancer, Ewing's sarcoma, respond to a drug that is...

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2012-03-13 08:48:17

In trying to unlock the potential of retinoids to treat patients with acute myeloid leukemia (AML), scientists have found the antidepressant called tranylcypromine (TCP) may be the key. Many types of AML can be treated with the retinoid all-trans retinoic acid (ATRA), a vitamin A-derivative. However, ATRA has not been shown to be effective with the more common types of AML. Arthur Zelent, PhD and his team at the Institute of Cancer Research (ICR) have been studying TCP to unlock the...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.