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Latest Insulin degrading enzyme Stories

2014-07-11 13:26:52

IOS Press Monitoring formation of amylin plaques using 2-D IR spectroscopy, scientists have observed the creation of temporary intermediate structures, which may explain why proteins aggregate into toxic plaques Amyloid diseases, such as Alzheimer's disease, type 2 diabetes, cataracts, and the spongiform encephalopathies, all share the common trait that proteins aggregate into long fibers which then form plaques. Yet in vitro studies have found that neither the amylin monomer...

Specific Mechanisms Of Alzheimer’s Disease Countered By Cocoa Extract
2014-06-24 03:38:45

Mount Sinai Hospital Insights into mechanisms behind cocoa’s benefit may lead to new treatments or dietary regimens A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer’s disease patients’ brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer’s Disease (JAD). Specifically, the study results, using mice...

2014-05-27 23:06:05

MetLife Foundation has announced the recipients of the 2014 MetLife Foundation Awards for Medical Research: Riqiang Yan, Ph.D., vice chair of the Department of Neurosciences, Lerner Research Institute, Cleveland Clinic; and Lary C. Walker, Ph.D., research professor of neuropharmacology and neurologic diseases and associate professor of neurology, Yerkes National Primate Research Center, Emory University (Atlanta, GA) and Mathias Jucker, Ph.D., full professor, Hertie Institute for Clinical...

2014-04-25 04:21:34

SANTA CLARA, California and LONDON, April 25, 2014 /PRNewswire/ -- Atypon(R) [http://www.atypon.com ] and Figshare [http://www.figshare.com ] today announced a partnership to make authors' supplemental data more discoverable on publishers' Literatum [http://atypon.com/literatum/overview.php ]-powered websites. Publishers on Literatum 14.1 [http://www.atypon.com/literatum/whats-new.php ], the newest generation of Atypon's flagship platform for professional and scholarly...

2014-04-08 08:32:29

SYDNEY, April 8, 2014 /PRNewswire/ -- For the second year in a row, ide's innovative and world-class product design has been recognised at the 2014 Medical Design Excellence Awards (MDEA). The AtomoRapid(TM) HIV is one of three finalists in the In Vitro Diagnostic Products and Systems category of this year's MDEA, the Medtech industry's leading international awards. AtomoRapid(TM) HIV is the world's first integrated rapid HIV blood test, offering a simple, reliable solution for...

Gordon Supercomputer Helps Guide New Drug Designs
2014-02-19 12:45:35

University of California, San Diego Single amyloid-beta monomers can pair up to form a variety of dimers that can aggregate into larger peptide rings that reside on cell membranes such as those pictured. This process has been implicated in the development of Alzheimer’s disease. This visualization shows the possible rings which have the most favorable energies of interactions with the membrane. The residues are colored white to represent apolar or hydrophobic areas, green for the polar...

2014-01-13 10:21:10

New Study Pinpoints Structural Effects of V44M and V44A Mutations New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. In a paper published January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations – V44M and V44A – known to cause FAD,...

2013-12-03 23:02:00

St. Jude Children’s Research Hospital scientists identify enzyme that could lead to better diagnosis and treatment of Alzheimer’s disease and related disorders. Memphis, Tenn. (PRWEB) December 03, 2013 St. Jude Children’s Research Hospital scientists have identified an enzyme that can halt or possibly even reverse the build-up of toxic protein fragments known as plaques in the brains of mice with Alzheimer’s disease. The research appeared in a recent edition of the scientific...

2013-10-16 11:36:40

New research led by Marco Prado, PhD, of Western University has identified a pathway used by the brain to try to protect itself from toxicity that occurs with Alzheimer's disease (AD). Prado and his colleagues at the Robarts Research Institute and at the A.C. Camargo Cancer Center in Brazil have done extensive work on the role of prion protein. They found that toxicity of amyloid-β peptides, one of the major culprits in AD, can be decreased by preventing it from interacting with the prion...

2013-09-23 23:26:46

Two rare mutations in the human gene that lead to the most common, late-onset variant of Alzheimer's have been identified by Chair Member of the Cure Alzheimer's Disease Research Consortium, Dr. Rudy Tanzi, bringing researchers closer to identifying a cure. Boston, MA (PRWEB) September 23, 2013 In a paper recently published in the prestigious journal Neuron, Harvard Medical School/Mass General Hospital Geneticist Dr. Rudy Tanzi, together with lead author, Dr. Jaehong Suh and their...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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