Latest Insulin-like growth factor 1 receptor Stories
Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling.
There are numerous specialized growth factors that are responsible for cells of different tissues of our body to divide and differentiate when needed.
Blocking a growth factor receptor cripples cancer growth in a form of T cell leukemia.
When the best therapies fail, drug combos offer new hope.
Insulin-like growth factor-I (IGF-I) is upregulated in human pancreatic cancer tissues but is not expressed in surrounding non-cancerous tissues.
A group of breast cancer drugs that had been deemed ineffective might be able to help a sub-group of breast cancer patients after all.Researchers at Emory University School of Medicine discovered through laboratory tests that hormones produced by adipocytes (fat cells) stimulate breast cancer cells to migrate and invade surrounding healthy tissue. A group of drugs called epithelial growth factor receptor (EGFR) inhibitors could block the stimulatory effects of the hormones."This group of...
Exelixis, Inc. (Nasdaq:EXEL) today reported preliminary phase 1 data from a dose-escalation trial of XL228 in patients with advanced malignancies (solid tumors, lymphoma, or multiple myeloma) for which standard therapies are no longer effective.
ImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, today announced that its disease-directed randomized Phase 2 clinical trial of IMC-A12, ImClone's fully human, IgG1 anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody, in women with advanced breast cancer has commenced patient enrollment.
Green tea appears to inhibit the spread of prostate cancer in a number of ways, says a study in the Dec. 1 issue of Cancer Research.
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