Latest Integral membrane protein Stories

2012-05-30 10:56:51

Salk scientists develop new technique for solving the structure of most popular targets for half of all drugs, potentially aiding discovery of new therapeutics A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods. The technique, developed by scientists at the Salk...

2010-10-28 13:43:35

Membrane proteins are of immense biological and pharmaceutical importance. But so far there are only a handful of cases in which the exact structure could be successfully determined. Scientists at Columbia University, New York, and Technische Universitaet Muenchen (TUM) have now succeeded in working out the structure of an important ion channel via the analysis of related proteins. The current issue of the journal Nature reports on their findings. Proteins are molecular machines that...

2008-10-07 15:00:41

A team of U.S. medical scientists has developed a potential new approach for the creation of more effective antibiotics. "As bacteria become more resistant to our current classes of antibiotics, there also has been a general lack of new targets for developing novel antibiotics," said University of Virginia Professor John Bushweller, who led the study. "Our discovery provides a starting point for a completely novel class of antibiotics, acting via a different mechanism." Bushweller and his...

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