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Latest Integral membrane proteins Stories

2012-07-13 08:20:01

Tokyo, July 13, 2012 - (JCN Newswire) - Eisai Co., Ltd. announced today that first data from clinical studies with E2609, a BACE (beta-site amyloid precursor protein-cleaving enzyme) inhibitor discovered in-house, will be presented during oral sessions at the Alzheimer's Association International Conference (AAIC) 2012, taking place in Vancouver, Canada from July 14 to 19, 2012. E2609 is a BACE inhibitor currently being developed by Eisai as a next-generation oral Alzheimer's disease...

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2012-07-13 07:06:17

Connie K. Ho for redOrbit.com - Your Universe Online 5 million. That´s the number of people in the U.S. suffering from Alzheimer´s disease, according to a recent CNN article. Scientists recently announced that they had discovered a gene that fights Alzheimer´s. This is a positive step forward as the gene could help develop treatments to fight the disorder. In the journal Nature, researchers explained how the gene that caused an early form of Alzheimer´s could also be...

2012-07-12 23:01:25

Sophion and CreaCell announced today that the two companies successfully demonstrated the performances of HEK-hKir2.1 cells on QPatch HT. (PRWEB) July 12, 2012 Inward rectifier potassium channels of the Kir2 subfamily are important determinants of the electrical activity of cardiac cells, and mutations of the Kir2.1 channels are associated with familial atrial fibrillation, Andersen-Tawil syndrome and short-QT syndrome. Because human Kir2.1 is a relevant target in preclinical cardiac...

Small Molecule Might Play Big Role In Alzheimer's Disease
2012-07-10 10:58:00

Simulations by UC Santa Barbara researchers improve understanding of plaque formation and suggest new diagnostic and treatment options Alzheimer's disease is one of the most dreaded and debilitating illnesses one can develop. Currently, the disease afflicts 6.5 million Americans and the Alzheimer's Association projects it to increase to between 11 and 16 million, or 1 in 85 people, by 2050. Cell death in the brain causes one to grow forgetful, confused and, eventually, catatonic....

2012-07-02 21:37:07

Research published today in Biomed Central's open access journal Journal of Neuroinflammation suggests that chronic inflammation can predispose the brain to develop Alzheimer's disease. To date it has been difficult to pin down the role of inflammation in Alzheimer's disease (AD), especially because trials of NSAIDs appeared to have conflicting results. Although the ADAPT (The Alzheimer`s Disease Anti-inflammatory Prevention Trial) trial was stopped early, recent results suggest that...

2012-06-27 17:29:28

In a recent Journal of Biological Chemistry "Paper of the Week," research led by Ayae Kinoshita at the Kyoto University Graduate School of Medicine in Japan reveals the benefits of exercise in combating Alzheimer's disease. The most common cause of dementia, Alzheimer's disease results in the loss of cognitive faculty. In the majority of cases, Alzheimer's disease occurs after age 65, and factors such as diet and exercise appear to play a role in its development, with high-fat diets as a...

2012-06-26 10:27:44

Scientists from Queen Mary, University of London have discovered a mechanism that controls the way that organisms breathe or photosynthesize, potentially paving the way for improved biofuel production. Writing in the journal PNAS, Dr Lu-ning Lu and Professor Conrad Mullineaux from Queen Mary's School of Biological and Chemical Sciences report that by exposing cells to different light conditions, they have changed the way in which electrons are transported. Professor Mullineaux explains:...

2012-06-20 11:13:47

Amyloid fibers in the brain are a hallmark of many neurodegenerative diseases, including Parkinson's disease, for which there are no effective treatments. These fibers result from aggregation of a specific protein in each disease–in Parkinson's, for example, the aggregated protein is called alpha-synuclein. Although amyloid fibers are implicated in numerous pathologies, they can also play beneficial, protective roles. In yeast, for example, they are associated with increased survival...

2012-06-16 00:48:48

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans. Researchers at the Peninsula College of Medicine and Dentistry, University of Exeter with colleagues in the National Institute on Aging in the USA and in Italy screened the expression levels of thousands of genes in blood samples from nearly 700 people. The telltale marker...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.