Quantcast

Latest Integral membrane proteins Stories

2011-06-23 19:52:26

A new advance by UCLA biochemists has brought scientists one step closer to developing treatments that could delay the onset of Alzheimer's disease and prevent the sexual transmission of HIV. The researchers report that they have designed molecular inhibitors that target specific proteins associated with Alzheimer's disease and HIV to prevent them from forming amyloid fibers, the elongated chains of interlocking proteins that play a key role in more than two dozen degenerative and often fatal...

2011-06-21 18:32:32

Maxim Bazhenov and Giri Krishnan used computational model to study epileptic seizures at the molecular level; research could lead to novel therapeutics for seizure disorder Researchers at the University of California, Riverside have made a discovery in the lab that could help drug manufacturers develop new antiepileptic drugs and explore novel strategies for treating seizures associated with epilepsy "“ a disease affecting about two million Americans. Neurons, the basic building blocks...

2011-06-15 21:16:51

Plant receptors use different signalling method than do animal receptors Every living plant cell and animal cell is surrounded by a membrane. These cellular membranes contain receptor molecules that serve as the cell's eyes and ears, and help it communicate with other cells and with the outside world. The receptor molecules accomplish three basic things in the communication process: 1) recognize an outside signal, 2) transport that signal across the cell's membrane and 3) initiate the reading...

2011-06-14 13:38:51

Researchers at North Carolina State University have figured out how copper induces misfolding in the protein associated with Parkinson's disease, leading to creation of the fibrillar plaques which characterize the disease. This finding has implications for both the study of Parkinson's progression, as well as for future treatments. The protein in question, alpha-synuclein, is the major component of fibrillar plaques found in Parkinson's patients. Researchers had already discovered that...

0c0ab842a69d7b3657aaeaa68ef620ea
2011-06-07 08:00:04

Researchers decode an important mechanism through which insulin in the hypothalamus controls the body's energy balance Fat-rich food makes you fat. Behind this simple equation lie complex signaling pathways, through which the neurotransmitters in the brain control the body's energy balance. Scientists at the Cologne-based Max Planck Institute for Neurological Research and the Cluster of Excellence in Cellular Stress Responses in Ageing-associated Diseases (CECAD) at the University of Cologne...

2011-06-03 12:19:13

Using a high-resolution single-molecule study technique, University of Illinois researchers have seen the very subtle differences between two branches of an important family of neurotransmitter-gated ion channels. Professor Claudio Grosman and research scientist Gisela Cymes published their work in the journal Nature. Nicotinic-type receptors are proteins embedded in the membranes of nerve and muscle cells that regulate activity. A neurotransmitter, such as acetylcholine, triggers a small...

2011-05-31 21:15:59

Researchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, E64d, not only reduces the build-up of ÃŽ²-amyloid (AÃŽ²) in the brains of animal models for Alzheimer's disease, but also results in a substantial improvement in memory deficit. A paper detailing the findings has been published as an...

2011-05-31 12:36:52

Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. The study appears in the May 30 issue of The Journal of Cell Biology (www.jcb.org). Like a movie with an alternate ending, a protein can come in more than one version. Although scientists have identified numerous proteins and RNAs that influence alternative splicing, they haven't deciphered...

2011-05-31 06:47:52

(Ivanhoe Newswire) "“ Researchers pinpoint a small RNA that triggers cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. Like a movie with an alternate ending, a protein can come in more than one version. Although scientists have identified numerous proteins and RNAs that influence alternative splicing, they haven't deciphered how cells fine-tune the process to produce specific...

2011-05-18 00:10:16

An essential component of animal nervous systems"”sodium channels"”evolved prior to the evolution of those systems, researchers from The University of Texas at Austin have discovered. "The first nervous systems appeared in jellyfish-like animals six hundred million years ago or so," says Harold Zakon, professor of neurobiology, "and it was thought that sodium channels evolved around that time. We have now discovered that sodium channels were around well before nervous systems...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.