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Specific Mechanisms Of Alzheimer’s Disease Countered By Cocoa Extract
2014-06-24 03:38:45

Mount Sinai Hospital Insights into mechanisms behind cocoa’s benefit may lead to new treatments or dietary regimens A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer’s disease patients’ brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer’s Disease (JAD). Specifically, the study results, using mice...

2014-05-28 08:26:44

- Preclinical data demonstrates reduction of Alzheimer's brain deficits to lower toxic Amyloid-beta and restored synaptic loss - PLANTATION, Fla., May 28, 2014 /PRNewswire/ -- Neurotrope, Inc. (OTCQB: NTRP) announced today the publication of positive human cell culture and mouse model data of Bryostatin 1 in two peer reviewed journals: PLOS One and the Journal of Pharmacology and Experimental Therapeutics. Neurotrope's lead drug candidate, Bryostatin 1, a potent activator of the...

2014-05-27 23:06:05

MetLife Foundation has announced the recipients of the 2014 MetLife Foundation Awards for Medical Research: Riqiang Yan, Ph.D., vice chair of the Department of Neurosciences, Lerner Research Institute, Cleveland Clinic; and Lary C. Walker, Ph.D., research professor of neuropharmacology and neurologic diseases and associate professor of neurology, Yerkes National Primate Research Center, Emory University (Atlanta, GA) and Mathias Jucker, Ph.D., full professor, Hertie Institute for Clinical...

2014-05-21 16:27:02

PITTSBURGH, May 21, 2014 /PRNewswire/ -- Cognition Therapeutics Inc. (CogRx), an innovative research and drug discovery organization focused on the development of novel disease-modifying therapeutics for neurodegenerative diseases, announced today that its small molecule soluble Abeta receptor antagonist program for the treatment of Alzheimer's disease (AD) has been selected for funding by the National Institute on Aging (NIA)/NIH Alzheimer's Disease Drug Development Program (U01)....

2014-05-21 11:48:44

Saint Louis University A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease. The molecule also reduced inflammation in the part of the brain responsible for learning and memory. The paper, authored by a team of scientists led by Susan Farr, Ph.D., research professor of geriatrics at Saint Louis University,...

2014-04-30 12:05:19

This Week in Molecular Biology and Evolution Take a muscle cell, modify it over millions of years, and you end up with an exciting and literally shocking evolutionary result: the electric fish. Electric fish have evolved several times in varying levels of complexity. Two groups of electric fish, one in Africa (Mormyroids) and one in South America (Gymnotiforms), have independently evolved sophisticated communication systems using these cells. By emitting and sensing weak electrical...

2014-04-25 10:11:04

Leaps orders of magnitude beyond existing tools -- NIH study Scientists have bioengineered, in neurons cultured from rats, an enhancement to a cutting edge technology that provides instant control over brain circuit activity with a flash of light. The research funded by the National Institutes of Health adds the same level of control over turning neurons off that, until now, had been limited to turning them on. "What had been working through a weak pump can now work through a highly...

2014-04-25 10:04:46

Much-needed tool for neuroscience emerges after years of work Nearly a decade ago, the era of optogenetics was ushered in with the development of channelrhodopsins, light-activated ion channels that can, with the flick of a switch, instantaneously turn on neurons in which they are genetically expressed. What has lagged behind, however, is the ability to use light to inactivate neurons with an equal level of reliability and efficiency. Now, Howard Hughes Medical Institute (HHMI) scientists...

2014-04-21 13:49:52

Compounds identified that stabilize retromer protein complex, which protects neurons from amyloid-beta A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating...

2014-04-14 14:20:45

Alzheimer's disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government's annual revenues. Unfortunately, it has proven very difficult to develop drugs capable of ameliorating the disease. After a tremendous burst of progress in the 1990s, the pace of discoveries has slowed. Dr. Saido believes that...


Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin