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Latest Integral membrane proteins Stories

2014-04-25 10:11:04

Leaps orders of magnitude beyond existing tools -- NIH study Scientists have bioengineered, in neurons cultured from rats, an enhancement to a cutting edge technology that provides instant control over brain circuit activity with a flash of light. The research funded by the National Institutes of Health adds the same level of control over turning neurons off that, until now, had been limited to turning them on. "What had been working through a weak pump can now work through a highly...

2014-04-25 10:04:46

Much-needed tool for neuroscience emerges after years of work Nearly a decade ago, the era of optogenetics was ushered in with the development of channelrhodopsins, light-activated ion channels that can, with the flick of a switch, instantaneously turn on neurons in which they are genetically expressed. What has lagged behind, however, is the ability to use light to inactivate neurons with an equal level of reliability and efficiency. Now, Howard Hughes Medical Institute (HHMI) scientists...

2014-04-21 13:49:52

Compounds identified that stabilize retromer protein complex, which protects neurons from amyloid-beta A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating...

2014-04-14 14:20:45

Alzheimer's disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government's annual revenues. Unfortunately, it has proven very difficult to develop drugs capable of ameliorating the disease. After a tremendous burst of progress in the 1990s, the pace of discoveries has slowed. Dr. Saido believes that...

2014-04-10 23:03:15

The findings from The Scripps Research Institute may lead to new insights into immune deficiency, stroke and diabetes. La Jolla, California (PRWEB) April 10, 2014 A team led by scientists at The Scripps Research Institute (TSRI) has identified a long-sought protein that facilitates one of the most basic functions of cells: regulating their volume to keep from swelling excessively. The identification of the protein, dubbed SWELL1, solves a decades-long mystery of cell biology and points to...

2014-04-03 08:22:27

DUBLIN, Apr. 03, 2014 /PRNewswire/ -- Research and Markets ( http://www.researchandmarkets.com/research/gw6znv/the_engineered ) has announced the addition of the "The Engineered T-Cell Receptor in Fusion Proteins, Antibodies & Cells: Emerging Opportunities for the Biopharmaceutical Industry" report to their offering. (Logo:http://photos.prnewswire.com/prnh/20130307/600769) A Comparative Analysis And Assessment Of TCR Technologies, Pipelines And Companies From An Industry Perspective...

2014-04-01 15:11:54

KIT computer models explain how ion channels in cell membranes react to light / light switch for nerve cells as a sensitive tool of research Networked nerve cells are the control center of organisms. In a nematode, 300 nerve cells are sufficient to initiate complex behavior. To understand the properties of the networks, re-searchers switch cells on and off with light and observe the resulting behavior of the organism. In the Science journal, sci-entists now present a protein that...

2014-03-20 23:22:46

ChanTest announces the unveiling of new, ground-breaking assays in ion channel research to support more efficient and cost-effective drug discovery at the Society of Toxicology (SOT) Annual Meeting starting Monday in Phoenix, Arizona. Cleveland, Ohio (PRWEB) March 20, 2014 On Monday, March 24, ChanTest will host a session on Assays for Assessing Cardiotoxicity, Contractility, and ECG-Like Aberrations in Stem Cell-Derived Cardiomyocytes from 9:15 am – 10:15 am in Room 106C West at the...

2014-03-05 12:27:31

LEARN Project will Track Cognitive Change in a Comparison Group of Older Individuals, and Initiate the First Tau Imaging Study in a Longitudinal Prevention Trial CHICAGO, March 5, 2014 /PRNewswire-USNewswire/ -- The Alzheimer's Association today announced its largest ever research grant - $8 million over four years - to support the Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN) study as a companion study to the Anti-Amyloid Treatment in Asymptomatic Alzheimer's...

2014-03-05 10:36:54

After a decade of debate, scientists have a clear picture of a controversial protein that helps regulate heart contractions Brandeis University researchers have unlocked a controversial structure in heart cells responsible for regulating heart contractions. For years, scientists have debated how many KCNE1 proteins are required to build a potassium ion channel, theorizing anywhere between one and 14. Now, Brandeis University researchers found that these channels are built with two E1s....


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snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.