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Latest Integral membrane proteins Stories

2013-10-17 10:36:21

Even for elderly people with no signs of dementia, those with hardening of the arteries are more likely to also have the beta-amyloid plaques in the brain that are a hallmark of Alzheimer's disease, according to a study published in the October 16, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. "This is more evidence that cardiovascular health leads to a healthy brain," said study author Timothy M. Hughes, PhD, of the University of Pittsburgh....

2013-10-16 11:36:40

New research led by Marco Prado, PhD, of Western University has identified a pathway used by the brain to try to protect itself from toxicity that occurs with Alzheimer's disease (AD). Prado and his colleagues at the Robarts Research Institute and at the A.C. Camargo Cancer Center in Brazil have done extensive work on the role of prion protein. They found that toxicity of amyloid-β peptides, one of the major culprits in AD, can be decreased by preventing it from interacting with the prion...

2013-10-07 08:25:05

MONTREAL, Oct. 7, 2013 /CNW/ - Results from two new studies add to the body of evidence that supports Cognigram(TM) as a sensitive assessment to detect and monitor cognitive decline over time, namely in healthy individuals and adults with mild cognitive impairment (MCI) that are carriers of a biological marker in the brain - Ab amyloid.(1,2) Data from two studies were presented at the Canadian Conference on Dementia (CCD), in Vancouver, British Columbia, between October 3 and 5....

2013-09-28 00:20:25

Company Remains Committed to Alzheimer's Disease Research and Development to Bring Innovative New Products to Patients Who Need Them Most INDIANAPOLIS, Sept. 27, 2013 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) is disappointed that the Centers for Medicare & Medicaid Services (CMS) has denied patient access to beta-amyloid imaging agents, such as Amyvid(TM) (Florbetapir F 18 Injection). This final decision is not only contrary to expert opinion and published Appropriate Use Criteria...

2013-09-23 23:26:46

Two rare mutations in the human gene that lead to the most common, late-onset variant of Alzheimer's have been identified by Chair Member of the Cure Alzheimer's Disease Research Consortium, Dr. Rudy Tanzi, bringing researchers closer to identifying a cure. Boston, MA (PRWEB) September 23, 2013 In a paper recently published in the prestigious journal Neuron, Harvard Medical School/Mass General Hospital Geneticist Dr. Rudy Tanzi, together with lead author, Dr. Jaehong Suh and their...

Alzheimer's Development And Progression Seen Through New Imaging Agents
2013-09-20 04:27:08

redOrbit Staff & Wire Reports - Your Universe Online Researchers have created a new class of imaging agents that could allow them to view the biological processes that occur in the brain during the development and progression of Alzheimer’s disease, according to research appearing in Wednesday’s edition of the journal Neuron. Senior author Dr. Makoto Higuchi of the National Institute of Radiological Sciences in Japan and colleagues have developed a fluorescent compound that...

2013-09-04 12:30:11

NEW YORK, Sept. 4, 2013 /PRNewswire/ -- Oligomerix, Inc., a privately held company pioneering the development of disease modifying therapeutics for Alzheimer's disease (AD) and related neurodegenerative disorders, announced today the publication of a collaborative study in the peer-reviewed International Journal of Cell Biology that found tau oligomer trimers were specifically toxic to neuronal cultures. The study, titled "Trimeric tau is toxic to human neuronal cells at low...

2013-08-22 10:27:23

Survey suggests guidance and counseling need to be in place A leading group of Alzheimer's researchers contends that, as biomarkers to detect signals of the disease improve at providing clinically meaningful information, researchers will need guidance on how to constructively disclose test results and track how disclosure impacts both patients and the data collected in research studies. A survey conducted by a group including experts from the Perelman School of Medicine at the University...

Lab-made Complexes Absorb More Sunlight
2013-08-21 15:47:02

Washington University in St. Louis A ring of protein and pigments, half synthetic and half natural, can be used to quickly prototype light-harvesting antennas that absorb more sunlight than fully natural ones In diagrams it looks like a confection of self-curling ribbon with bits of bling hung off the ribbon here and there. In fact it is a carefully designed ring of proteins with attached pigments that self-assembles into a structure that soaks up sunlight. The scientists who made it...

Iron Accumulation Contributes To Alzheimer's Disease
2013-08-21 04:32:35

redOrbit Staff & Wire Reports - Your Universe Online Another day, another essential mineral linked to Alzheimer's disease. On the heels of a University of Rochester Medical Center (URMC) Department of Neurosurgery study which found that copper could factor into the onset and progression of the neurodegenerative condition, a second group of scientists has published research suggesting that iron accumulation could be one of the core contributing factors leading to the onset of the...