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Latest Integral membrane proteins Stories

Copper Linked To Onset Of Alzheimer's Disease
2013-08-20 05:03:30

redOrbit Staff & Wire Reports - Your Universe Online An element that is essential to all living organisms could also be one of the primary environmental factors that can lead to the onset of Alzheimer’s disease, according to new research appearing in Monday’s edition of the journal Proceedings of the National Academy of Sciences. Copper, which is a key constituent of the respiratory enzyme complex cytochrome c oxidase, also appears to enhance the progression of the...

2013-08-08 09:39:19

Though one might think the brains of people who develop Alzheimer's disease (AD) possess building blocks of the disease absent in healthy brains, for most sufferers, this is not true. Every human brain contains the ingredients necessary to spark AD, but while an estimated 5 million Americans have AD – a number projected to triple by 2050 – the vast majority of people do not and will not develop the devastating neurological condition. For researchers like...

2013-08-06 23:20:20

On September 27, 2013, ChanTest will host a User Meeting entitled "Partnerships in Drug Discovery." The meeting will be held at the Westin Boston Waterfront Hotel. Cleveland, OH (PRWEB) August 06, 2013 Partnerships between industry and vendors have a positive impact on the drug discovery industry when the right companies come together, as they allow for innovation and optimize the process of identifying the right drugs faster and more effectively. On Friday, September 27, 2013,...

Water Molecules Control Long Post-activation Recovery Period Of Potassium Channels
2013-07-29 08:51:57

University of Chicago Medical Center Just 12 molecules of water cause the long post-activation recovery period required by potassium ion channels before they can function again. Using molecular simulations that modeled a potassium channel and its immediate cellular environment, atom for atom, University of Chicago scientists have revealed this new mechanism in the function of a nearly universal biological structure, with implications ranging from fundamental biology to the design of...

2013-07-26 14:12:08

Study first to use 'structural' approach in hunt for amyloid-inhibiting agents UCLA chemists and molecular biologists have for the first time used a "structure-based" approach to drug design to identify compounds with the potential to delay or treat Alzheimer's disease, and possibly Parkinson's, Lou Gehrig's disease and other degenerative disorders. All of these diseases are marked by harmful, elongated, rope-like structures known as amyloid fibrils, linked protein molecules that form...

Genetic Interactions In Alzheimers Brain
2013-07-25 09:20:15

Rebekah Eliason for redOrbit.com - Your Universe Online Researchers at Columbia University Medical Center recently discovered key molecular pathways in the brain that lead to late-onset Alzheimer's disease, the most common form of the disorder. Both systems biology and cell biology tools were used in this new study that presents a unique approach to Alzheimer's disease research as well as new possibilities for drug targets. Most Alzheimer research is based on laboratory studies of...

2013-07-24 08:29:58

CLEVELAND, July 24, 2013 /PRNewswire/ -- ChanTest proudly announces that CEO, President and Founder, Arthur "Buzz" Brown, M.D., Ph.D. has been named the recipient of the prestigious Distinguished Service Award by the Safety Pharmacology Society (SPS). The following statement was issued by the SPS, "The award is in recognition of Dr. Brown's significant scientific contributions to many areas of Safety Pharmacology, most notably contributions to ion channels and their relationship to...

2013-07-17 16:27:04

BOSTON, July 17, 2013 /PRNewswire-USNewswire/ -- New studies reported at the Alzheimer's Association International Conference 2013 (AAIC(®) 2013) in Boston cover the spectrum of Alzheimer's disease and dementia research, including novel treatment and prevention strategies, possible new risk factors, advances in early detection and diagnosis, and an updated model of disease progression. The Alzheimer's Association International Conference is the premier annual forum for...

2013-07-16 16:14:30

Additional data from GAP study presented by Dr. Norman Relkin at Alzheimer's Association International Conference Weill Cornell Medical College neurologist Dr. Norman Relkin reported new findings today from the Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in mild to moderate Alzheimer's disease at the Alzheimer's Association International Conference (AAIC) in Boston, Mass. While the primary study outcomes were negative, observations from the subgroup analyses include whether...

2013-07-16 15:42:18

Brandeis scientists bring us a step closer to understanding how to control cancer cells without harming healthy ones The nasty side effects of radiation and chemotherapy are well known: fatigue, hair loss and nausea, to name a few. Cancer treatment can seem as harsh as the disease because it can't differentiate healthy cells from cancerous cells, killing both. But what if there were a way to control or stop the growth of cancer cells without harming other cells? Brandeis biologist...