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Latest Integral membrane proteins Stories

2013-06-13 00:22:58

NEW YORK, June 12, 2013 /PRNewswire-USNewswire/ -- The Alzheimer's Drug Discovery Foundation (ADDF) announced that it has awarded follow-on funding of $298,500 to Madera Biosciences, Inc. to further develop its small molecule drugs designed to clear accumulated beta-amyloid from the brain and thus halt or reverse the progression of Alzheimer's disease. Madera has identified a series of proprietary, small molecule compounds that increase the expression of apolipoprotein E (apoE), which has...

2013-05-29 10:13:32

Scientists at the University of Liverpool and Callaghan Innovation in New Zealand have developed a new chemical approach to help harness the natural ability of complex sugars to treat Alzheimer's disease. The team used a new chemical method to produce a library of sugars, called heparan sulphates, which are known to control the formation of the proteins in the brain that cause memory loss. Heparan sulphates are found in nearly every cell of the body, and are similar to the natural...

Promising Alzheimer’s Drug Fails In Second Test Round
2013-05-24 12:47:59

Brett Smith for redOrbit.com - Your Universe Online While the recent failure of a potential Alzheimer´s disease treatment is bad news for patients, it serves as an important reminder of the importance of thorough pre-clinical testing of experimental drugs before beginning human trials. According to a group of University of Florida researchers, tests of the anti-cancer drug bexarotene failed to stop the formation of the amyloid brain plaques that are associated with Alzheimer´s...

2013-05-22 12:30:34

Funds to Advance Research Across Key Tau Programs in Alzheimer's disease NEW YORK, May 22, 2013 /PRNewswire/ -- Oligomerix, Inc., a privately held company pioneering the development of disease modifying therapeutics for Alzheimer's disease (AD) and related neurodegenerative disorders, announced today the completion of its Series B financing, which includes both issuance of new convertible preferred shares and warrants that would represent approximately $2.8M in new investments in...

2013-05-15 23:03:02

MetLife Foundation today announced the recipients of its 2013 Awards for Medical Research in Alzheimer´s Disease: Yueming Li, Ph.D., member and professor, Sloan-Kettering Institute and director and professor, Graduate Program in Pharmacology, Weill Medical College of Cornell University, and Lennart Mucke, M.D., director, Gladstone Institute of Neurological Disease, Joseph B. Martin Distinguished Professor of Neuroscience and professor of Neurology, University of California, San...

Researchers Slow Alzheimer's, Improve Memory In Mice Using Novel Drug
2013-05-14 16:02:24

Brett Smith for redOrbit.com - Your Universe Online Many Alzheimer´s disease researchers are focused on stopping the buildup of amyloid plaques, dense protein deposits that are a telltale sign of the debilitating disease. However, a group of scientists from the Salk Institute for Biological Studies decision to think outside the box and pursue a different treatment strategy has paid off. According to their report in the journal Alzheimer´s Research and Therapy, the Salk team...

2013-05-03 23:17:21

“Outsourced Ion Channel Testing Trends 2013” is the new market research report added to ReportsnReports.com store. Dallas, Texas (PRWEB) May 03, 2013 This market report summarizes the results of global web-based benchmarking survey on outsourced ion channel testing carried out in April 2013. The full report provides the data, details of the breakdown of the responses for each question, its segmentation and the estimates for the future (2015). It also highlights some interesting...

Researchers Find Alzheimer’s Biomarkers
2013-05-01 14:21:32

Brett Smith for redOrbit.com - Your Universe Online Researchers from Australia´s Commonwealth Scientific and Industrial Research Organisation“¯(CSIRO) are reporting significant progress in developing a blood test that can predict the onset of Alzheimer´s in an individual. According to their report in the journal Molecular Psychiatry, the researchers said they have identified several biomarkers that are associated with the toxic build-up of beta amyloid, a brain...

2013-04-29 14:06:58

For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. Since tumors are highly dependent on the transportation of nutrients in order to be able to grow rapidly, the researchers are hoping that the study published in the scientific magazine Nature Structural & Molecular Biology will form the basis for new strategies to fight cancer cells. In order to be able to...

Alzheimer's Disease: Protective Gene Variant Sheds Light On Potential New Treatment
2013-04-26 04:44:04

redOrbit Staff & Wire Reports - Your Universe Online New research published Thursday in the journal Neuron sheds new light on the molecular causes of Alzheimer´s disease, while also revealing a potential new therapy which could help prevent cognitive decline and brain damage during the early stages of the neurodegenerative disorder. The study focuses on a variant of a gene known as CD33, which typically contributes to Alzheimer´s disease by inhibiting the ability of a...