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Latest Integral membrane proteins Stories

Water Molecules Control Long Post-activation Recovery Period Of Potassium Channels
2013-07-29 08:51:57

University of Chicago Medical Center Just 12 molecules of water cause the long post-activation recovery period required by potassium ion channels before they can function again. Using molecular simulations that modeled a potassium channel and its immediate cellular environment, atom for atom, University of Chicago scientists have revealed this new mechanism in the function of a nearly universal biological structure, with implications ranging from fundamental biology to the design of...

2013-07-26 14:12:08

Study first to use 'structural' approach in hunt for amyloid-inhibiting agents UCLA chemists and molecular biologists have for the first time used a "structure-based" approach to drug design to identify compounds with the potential to delay or treat Alzheimer's disease, and possibly Parkinson's, Lou Gehrig's disease and other degenerative disorders. All of these diseases are marked by harmful, elongated, rope-like structures known as amyloid fibrils, linked protein molecules that form...

Genetic Interactions In Alzheimers Brain
2013-07-25 09:20:15

Rebekah Eliason for redOrbit.com - Your Universe Online Researchers at Columbia University Medical Center recently discovered key molecular pathways in the brain that lead to late-onset Alzheimer's disease, the most common form of the disorder. Both systems biology and cell biology tools were used in this new study that presents a unique approach to Alzheimer's disease research as well as new possibilities for drug targets. Most Alzheimer research is based on laboratory studies of...

2013-07-16 16:14:30

Additional data from GAP study presented by Dr. Norman Relkin at Alzheimer's Association International Conference Weill Cornell Medical College neurologist Dr. Norman Relkin reported new findings today from the Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in mild to moderate Alzheimer's disease at the Alzheimer's Association International Conference (AAIC) in Boston, Mass. While the primary study outcomes were negative, observations from the subgroup analyses include whether...

2013-07-16 15:42:18

Brandeis scientists bring us a step closer to understanding how to control cancer cells without harming healthy ones The nasty side effects of radiation and chemotherapy are well known: fatigue, hair loss and nausea, to name a few. Cancer treatment can seem as harsh as the disease because it can't differentiate healthy cells from cancerous cells, killing both. But what if there were a way to control or stop the growth of cancer cells without harming other cells? Brandeis biologist...

2013-07-08 12:09:26

UConn researchers shed new light on how cellular transport systems harness energy to perform their work inside the cell Using highly sensitive fluorescent probes, a team of scientists from the University of Connecticut has captured the never-before-seen structural dynamics of an important protein channel inside the cell's primary power plant – the mitochondrion. The UConn team's study found that the channel complex - known as the translocase of the inner mitochondrial...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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