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Latest Interferon-gamma Stories

2013-07-10 19:27:25

Researchers at UT Southwestern Medical Center report the identification of a new cellular source for an important disease-fighting protein used in the body's earliest response to infection. The protein interferon-gamma (IFN-γ) keeps viruses from replicating and stimulates the immune system to produce other disease-fighting agents. Neutrophils, the newly identified cellular source of the protein, are the major component of the pus that forms around injured tissue. The...

Why Koalas Get Chlamydia
2013-04-10 15:04:06

Michael Harper for redOrbit.com — Your Universe Online Blame it on their small stature. Blame it on their soft fur. For what could be a myriad of reasons, Koalas would almost certainly win the “Most Cuddly” award amongst all of the familiar marsupials. Sadly, like all other creatures — cute and ugly alike — Koalas also have a tendency to get sick from time to time. According Dr. Adam Polkinghorne and a host of researchers with Queensland University of...

2012-08-23 10:56:29

Autoantibody may cause susceptibility to opportunistic infections A clinical study led by National Institutes of Health investigators has identified an antibody that compromises the immune systems of HIV-negative people, making them susceptible to infections with opportunistic microbes such as nontuberculous mycobacteria (NTM). In this study conducted at hospitals in Thailand and Taiwan, the researchers found that the majority of study participants with opportunistic infections made an...

2012-01-26 11:35:41

A new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology. The research, published online on January 26th in the journal Immunity by Cell Press, provides key insight into mechanisms that underlie the development of autoimmune disease and may lead to more effective strategies for therapeutic intervention. There are multiple intracellular sensors that detect viral...

2011-12-02 12:57:31

Traumatic brain injury is associated with a profound suppression of the patient's ability to fight infection. At the same time the patient also often suffers hyper-inflammation, due to the brain releasing glucocorticoids in response to the injury. New research published in BioMed Central's open access journal Critical Care shows that including probiotics with nutrients, supplied via the patient's feeding tube, increased interferon levels, reduced the number of infections, and even reduced the...

2011-08-10 22:35:14

Discovery has implications for autoimmune diseases, HIV infection and possibly in cancer as a biomarker and in the development of new treatments New research led by Derya Unutmaz, MD associate professor, the Departments of Pathology, Medicine, and Microbiology at NYU School of Medicine and Mark Sundrud, PhD, of Tempero Pharmaceuticals, Inc., has identified a novel sensory pathway that modulates the potency of Th17 cell responses. The new research is highlighted in the August 8th online...

2011-07-22 14:50:09

St. Jude Children's Research Hospital scientists show that the molecule serves as a bridge between the two arms of the immune system that provides a new mechanism guiding T cell differentiation St. Jude Children's Research Hospital investigators have identified a signaling molecule that functions like a factory supervisor to ensure that the right mix of specialized T cells is available to fight infections and guard against autoimmune disease. The research also showed the molecule, phosphatase...

2011-05-16 18:26:17

Children's Hospital of Philadelphia study in animals: Immune system proteins might protect children from rare, deadly inflammation By analyzing complex interactions of the immune system in an animal study, pediatric researchers have found potential tools for controlling a life-threatening condition called a cytokine storm that may strike children who have juvenile arthritis and other autoimmune diseases. In a cytokine storm, the body's immune system rages out of control, resulting in...

2009-10-22 14:41:00

Immunologists at the University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC and the have found a unique quirk in the way the immune system fends off bacteria called Francisella tularensis, which could lead to vaccines that are better able to prevent tularemia infection of the lungs. Their findings were published today in the early, online version of Immunity. F. tularensis is an intracellular pathogen that infects cells in the lungs called macrophages,...

2009-03-05 08:15:46

Montreal, March 4th, 2009 "“ While interferon gamma sounds like an outer space weapon, it's actually a hormone produced by our own bodies, and it holds great promise to repair bones affected by osteoporosis. In a new study published in the journal Stem Cells, researchers from the Research Institute of the McGill University Health Centre explain that tweaking a certain group of multipotent stem cells (called mesenchymal stem cells) with interferon (IFN) gamma may promote bone growth."We...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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