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Latest Interferon Stories

2013-04-12 13:41:20

Blocking a key protein boosts body's ability to clear chronic infection UCLA scientists have shown that temporarily blocking a protein critical to immune response actually helps the body clear itself of chronic infection. Published in the April 12 edition of Science, the finding suggests new approaches to treating persistent viral infections like HIV and hepatitis C. The research team studied type-1 interferons (IFN-1), proteins released by cells in response to disease-causing organisms...

2013-04-12 13:25:11

The findings suggest a new approach to clearing infections from AIDS to hepatitis Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C. The study, reported in the April 12, 2013 issue of the journal Science, focused on the activity of the body's type 1 interferon (IFN-I) proteins. Since its discovery over 50 years ago,...

Why Koalas Get Chlamydia
2013-04-10 15:04:06

Michael Harper for redOrbit.com — Your Universe Online Blame it on their small stature. Blame it on their soft fur. For what could be a myriad of reasons, Koalas would almost certainly win the “Most Cuddly” award amongst all of the familiar marsupials. Sadly, like all other creatures — cute and ugly alike — Koalas also have a tendency to get sick from time to time. According Dr. Adam Polkinghorne and a host of researchers with Queensland University of...

2013-04-08 08:30:51

RIDGEFIELD, Conn., April 8, 2013 /PRNewswire/ -- Boehringer Ingelheim today announced that data from its pivotal STARTVerso(TM) 1 Phase 3 hepatitis C clinical trial have been accepted for oral presentation as a late-breaker at the International Liver Congress(TM) 2013: 48th Annual Meeting of the European Association for the Study of the Liver (EASL), taking place from April 24-28 in Amsterdam, The Netherlands. The STARTVerso(TM) 1 trial evaluated faldaprevir (BI 201335), an investigational...

2013-04-08 04:20:53

CORK, Ireland, April 8, 2013 /PRNewswire/ -- Janssen R&D Ireland (Janssen) announces that data will be presented on the investigational protease inhibitor simeprevir (TMC435) for the treatment of hepatitis C at The International Liver Congress 2013 of the European Association for the Study of the Liver (EASL), which will take place April 24 to 28 in Amsterdam, The Netherlands. These data presentations will include primary efficacy and safety results from the Phase 3 QUEST-1 study of...

2013-04-02 11:07:27

These findings will help inform vaccine design and interpretation of vaccine trials, and provide new insights into the basic biology of viral/host dynamics of infection. A new study by Los Alamos National Laboratory and University of Pennsylvania scientists defines previously unknown properties of transmitted HIV-1, the virus that causes AIDS. The viruses that successfully pass from a chronically infected person to a new individual are both remarkably resistant to a powerful initial human...

2013-03-28 16:25:12

-- Filing Based on Phase 3 Data in Treatment-Naïve and Treatment-Experienced Patients with Compensated Liver Disease -- RARITAN, N.J., March 28, 2013 /PRNewswire/ -- Janssen Research & Development, LLC (Janssen) today announced it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for simeprevir (TMC435), an investigational NS3/4A protease inhibitor, administered as a 150 mg capsule once daily with...

New Coronavirus Strain Adapted To Humans, Replicates Faster Than SARS
2013-02-19 11:24:51

Lawrence LeBlond for redOrbit.com - Your Universe Online A new strain of coronavirus, which has already infected 12 people and killed six in the past several months, has been found to breed in the human body much faster than SARS and can evade the immune system just as easily as a common cold. While health experts feel they may be able to develop immunotherapy to prevent the spread of the disease, they do not yet know how readily it does spread. Publishing their findings in the February...

HIV And Other Deadly Viruses Blocked By Natural Protein
2013-02-12 04:56:31

Jason Pierce, MSN, MBA, RN for redOrbit.com — Your Universe Online A study by a team of UCLA-led researchers, published in the journal Immunity in January 2013, may aid in the development of broad spectrum medications aimed at combating existing and newly emerging viral threats. Broad spectrum antivirals can be used to treat diseases caused by a variety of different viruses. The development of these medications is a domestic biodefense goal of the National Institute of Allergy and...

2013-01-31 15:18:11

People with hepatitis C and chronic liver disease who relapsed or failed to respond to initial treatment are unlikely to improve on interferon retreatment. In fact, they may face an increased risk of dying sooner, and are likely to experience a variety of adverse effects, according to an updated systematic review published in The Cochrane Library. Hepatitis C affects around 170 million people worldwide. In some cases, infection leads to chronic liver disease, liver failure or liver cancer,...


Latest Interferon Reference Libraries

0_9255b919f71eff1fd4202c1dbb1795d2
2011-01-12 15:49:29

Hepadnaviruses can cause liver infections in humans and animals. The two recognized genera are Genus Orthohepadnavirus and Genus Avihepadnavirus. It has a small genome of partially double-stranded, partially single stranded circular DNA. It is a group 7 virus that uses an RNA intermediate during replication. Most people who come into contact with the virus are able to clear the infection alone although some cannot and usually progress to fulminant hepatitis. It can cause sever liver...

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