Latest Intermittent preventive therapy Stories

Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower risk of low birth weight than the current standard 2-dose regimen, according to a review and meta-analysis of previous studies published in the February 13 issue of JAMA. "Intermittent preventive therapy with sulfadoxine-pyrimethamine to control malaria during pregnancy is used in 37...

Separate trials in Mali and Burkino Faso find substantial protective effect in children of combining IPTc with bednetsTwo separate studies "“ carried out in Burkina Faso and Mali"“ have found that combining intermittent preventive treatment of malaria in children (IPTc) with insecticide-treated bednets (ITNs) can substantially reduce the incidence of severe malaria.A third study carried out in The Gambia supported the findings, reporting that IPTc treatment was not only easily...

Three randomized controlled trials published in this week's PLoS Medicine show that intermittent preventive treatment of malaria in children adds to the benefit of sleeping under bednets and that this public health intervention is best delivered by community-based, volunteer village health workers.Two randomized controlled trials (with over 3000 children in each study) carried out by a team of researchers led by Diadier Diallo from the London School of Hygiene & Tropical Medicine, London,...

BARCELONA, Spain, September 17 /PRNewswire/ -- A third (30%) of malaria cases can be avoided in African infants using a safe, affordable and simple tool called Intermittent Preventive Treatment of malaria in Infants (IPTi) with the medicine sulphadoxine-pyrimethamine (SP), which can be delivered alongside existing childhood vaccination programmes.(i) Results of a meta-analysis examining six clinical trials in Africa for the malaria intervention which the World Health Organization...

Giving infants preventive treatment for malaria can reduce malaria and anaemia even in seasonal, high transmission areas such as Ghana, finds a study in this week's BMJ. But concern exists about a possible rebound when treatment is stopped, warn the authors. The study followed over 2,400 infants in Ghana who were given a preventive treatment for malaria or a placebo (dummy pill) when they received routine vaccinations and at 12 months of age. Preventive treatment reduced malaria by 25% and...