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Latest Internal ribosome entry site Stories

2012-07-20 01:50:16

New research has shown that a protein does something that scientists once thought impossible: It unfolds itself and refolds into a completely new shape. This protein, called RfaH, activates genes that allow bacterial cells to launch a successful attack on their host, causing disease. The researchers determined that RfaH starts out in its alpha form, composed of two spiral shapes. Later, in its beta form, it resembles spokes on a wheel and is called a barrel. When RfaH refolds, it...

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2012-03-14 11:08:41

In the beginning — of the ribosome, the cell's protein-building workbench — there were ribonucleic acids, the molecules we call RNA that today perform a host of vital functions in cells. And according to a new analysis, even before the ribosome's many working parts were recruited for protein synthesis, proteins also were on the scene and interacting with RNA. This finding challenges a long-held hypothesis about the early evolution of life. The study appears in the journal PLoS...

2012-03-12 20:00:01

In the beginning — of the ribosome, the cell's protein-building workbench — there were ribonucleic acids, the molecules we call RNA that today perform a host of vital functions in cells. And according to a new analysis, even before the ribosome's many working parts were recruited for protein synthesis, proteins also were on the scene and interacting with RNA. This finding challenges a long-held hypothesis about the early evolution of life. The "RNA world" hypothesis, first...

2010-10-29 19:16:52

Work could help unravel complexities of the cell and lead to new antibiotics and disease treatments A team from The Scripps Research Institute has revealed the first-ever pictures of the formation of cells' "protein factories." In addition to being a major technical feat on its own, the work could open new pathways for development of antibiotics and treatments for diseases tied to errors in ribosome formation. In addition, the techniques developed in the study can now be applied to other...

2008-11-14 09:00:34

CAMBRIDGE, England, November 14 /PRNewswire-FirstCall/ -- - European IRES Patent Upheld and UK Patent on Cell Screening Technology Granted - ("Stem Cell Sciences", "SCS", "the Company") IRES Patent Upheld in Appeal Hearing at the EPO Stem Cell Sciences plc (AIM:STEM, ASX:STC) announces that European patent no. 0695361 covering its IRES technology was upheld by the European Patent Office in Munich on 12th November 2008. The EPO Technical Board of Appeal dismissed objections against...

2008-11-13 03:00:16

Stem Cell Sciences, a provider of stem cells and stem cell technologies, has licensed internal ribosome entry site technology to a provider of genetically modified rat and mouse models for medical and pharmaceutical research. Under the terms of the multi-year agreement, which is non-exclusive and retroactive, the undisclosed partner will gain access to the internal ribosome entry site (IRES) technology for use in its own R&D activities. Under the terms of the license, Stem Cell Sciences...

2008-09-30 15:00:42

At the request of the Ontario Securities Commission ("OSC"), Philex Gold Inc. (TSX VENTURE: PGI) ("Philex" or "Company") issues the following clarification with respect to its previous press releases issued since June 14, 2004 regarding declared mineral resources for the Boyongan porphyry Cu/Au Deposit in the Philippines; a joint venture with Anglo American Exploration (Philippines) ("Anglo"). The 2004 announcement of an Inferred Mineral Resource of 219Mt at 0.51%Cu and 0.74g/t Au at a...

2005-07-04 18:30:00

A Howard Hughes Medical Institute investigator from Albany, New York, and an HHMI international research scholar from Buenos Aires, Argentina have combined their expertise to identify two peculiar features of the protein-making machinery of the parasite that causes Chagas disease. Their findings could help scientists develop a safe and effective drug for the disease, whose cardiac complications kill up to 30 percent of those infected. The unusual structure of the ribosome, published online...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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