Quantcast
Last updated on April 19, 2014 at 9:20 EDT

Latest Inward-rectifier potassium ion channel Stories

2012-07-12 23:01:25

Sophion and CreaCell announced today that the two companies successfully demonstrated the performances of HEK-hKir2.1 cells on QPatch HT. (PRWEB) July 12, 2012 Inward rectifier potassium channels of the Kir2 subfamily are important determinants of the electrical activity of cardiac cells, and mutations of the Kir2.1 channels are associated with familial atrial fibrillation, Andersen-Tawil syndrome and short-QT syndrome. Because human Kir2.1 is a relevant target in preclinical cardiac...

2010-07-02 19:59:04

The muscle weakness and coordination problems sometimes seen in patients with neonatal diabetes "“ a rare, inherited form of diabetes "“ are caused by problems in the brain rather than the muscles, according to research published today. The findings could pave the way for the development of improved treatments for the disease. Neonatal diabetes affects one in 100,000 infants in the UK. It usually begins in the first six months of a child's life and can be accompanied by...

2010-01-05 20:57:13

Many people have traded in their gas-guzzling old "clunkers" for newer and more efficient models or cut back on energy use at home by opting for Energy Star appliances and compact fluorescent light bulbs. But, when it comes to our muscles, a little less efficiency might be just what the doctor ordered, suggests a report in the January Cell Metabolism, a Cell Press publication. The researchers from the Mayo Clinic and the University of Iowa have new insight into an important "fuel gauge" in...

2010-01-05 20:48:37

Study reveals mechanism that adjusts fat burning Mayo researchers collaborating with investigators at the University of Iowa, University of Connecticut and New York University (NYU) have discovered a molecular mechanism that controls energy expenditure in muscles and helps determine body weight. Researchers say this could lead to a new medical approach in treating obesity. The findings appear in the journal Cell Metabolism. The energy-saving mechanism is controlled by ATP-sensitive potassium...

2009-09-08 14:38:13

By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. The mechanism involves a protein called ankyrin, which UI researchers previously linked to potentially fatal human heart arrhythmias. The findings, which appear this week in the Early Edition of the Proceedings of the National Academy of Sciences, may help identify new molecular targets for...