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Latest Ion channels Stories

chile peppers
2014-08-23 03:00:51

American Chemical Society As anyone who has bitten into a chili pepper knows, its burning spiciness — though irresistible to some — is intolerable to others. Scientists exploring the chili pepper’s effect are using their findings to develop a new drug candidate for many kinds of pain, which can be caused by inflammation or other problems. They reported their progress on the compound, which is being tested in clinical trials, in ACS’ Journal of Medicinal Chemistry. Laykea Tafesse...

chili peppers for tumors
2014-08-04 03:30:04

University of California, San Diego Health System Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin – the active ingredient in chili peppers – produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors. The findings are published in the August 1, 2014 issue of The Journal of Clinical Investigation. The receptor or ion channel,...

2014-07-10 23:06:41

ChanTest announces development of newly validated and re-engineered cells to support a critical element of the drug discovery process for the biopharmaceutical industry. Cleveland, Ohio (PRWEB) July 10, 2014 Understanding the need for better quality and higher consistency in ion channel-expressing cell lines, and the gap that currently exists in this area, ChanTest has recently developed new cells that expand its industry-leading portfolio of validated ion channel and GPCR cell lines....

2014-05-15 08:31:53

EVANSTON, Ill., May 15, 2014 /PRNewswire/ -- Naurex Inc. today announced that its president and chief executive officer, Norbert G. Riedel, PhD, will present at the UBS Global Healthcare Conference on Monday, May 19, 2014 at 1:00 p.m. EDT. Dr. Riedel will provide an overview of the company and discuss its two clinical-stage rapid-acting antidepressant drug candidates, GLYX-13 and NRX-1074. Last week Naurex reported positive top-line Phase 2b results for GLYX-13 and the advancement...

2014-05-13 08:31:28

SAN DIEGO, May 13, 2014 /PRNewswire/ -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE; Sorrento) a late-stage clinical oncology company developing new treatments for cancer and its associated pain, today announced that the U.S. Office of Orphan Products Development at the Food and Drug Administration (FDA) has approved the transfer of sponsorship of the Orphan Drug Designation for intrathecal resiniferatoxin (RTX) in the treatment of intractable pain in end-stage disease from the...

2014-04-30 12:05:19

This Week in Molecular Biology and Evolution Take a muscle cell, modify it over millions of years, and you end up with an exciting and literally shocking evolutionary result: the electric fish. Electric fish have evolved several times in varying levels of complexity. Two groups of electric fish, one in Africa (Mormyroids) and one in South America (Gymnotiforms), have independently evolved sophisticated communication systems using these cells. By emitting and sensing weak electrical...

2014-04-25 10:04:46

Much-needed tool for neuroscience emerges after years of work Nearly a decade ago, the era of optogenetics was ushered in with the development of channelrhodopsins, light-activated ion channels that can, with the flick of a switch, instantaneously turn on neurons in which they are genetically expressed. What has lagged behind, however, is the ability to use light to inactivate neurons with an equal level of reliability and efficiency. Now, Howard Hughes Medical Institute (HHMI) scientists...

2014-04-01 15:11:54

KIT computer models explain how ion channels in cell membranes react to light / light switch for nerve cells as a sensitive tool of research Networked nerve cells are the control center of organisms. In a nematode, 300 nerve cells are sufficient to initiate complex behavior. To understand the properties of the networks, re-searchers switch cells on and off with light and observe the resulting behavior of the organism. In the Science journal, sci-entists now present a protein that...

2014-03-20 23:22:46

ChanTest announces the unveiling of new, ground-breaking assays in ion channel research to support more efficient and cost-effective drug discovery at the Society of Toxicology (SOT) Annual Meeting starting Monday in Phoenix, Arizona. Cleveland, Ohio (PRWEB) March 20, 2014 On Monday, March 24, ChanTest will host a session on Assays for Assessing Cardiotoxicity, Contractility, and ECG-Like Aberrations in Stem Cell-Derived Cardiomyocytes from 9:15 am – 10:15 am in Room 106C West at the...

2014-03-05 10:36:54

After a decade of debate, scientists have a clear picture of a controversial protein that helps regulate heart contractions Brandeis University researchers have unlocked a controversial structure in heart cells responsible for regulating heart contractions. For years, scientists have debated how many KCNE1 proteins are required to build a potassium ion channel, theorizing anywhere between one and 14. Now, Brandeis University researchers found that these channels are built with two E1s....


Word of the Day
monteith
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'
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