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Latest Irving Weissman Stories

2012-03-27 08:38:49

Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody, according to a new study from the Stanford University School of Medicine. The antibody works by masking a protein flag on cancer cells that protects them from macrophages and other cells in the immune system. The scientists achieved the findings with human breast, ovarian, colon, bladder, brain, liver and prostate cancer samples. It is the first antibody...

2011-11-30 14:36:54

Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood and immune system. Understanding when and how these stem cells begin to falter as the years pass may explain why some diseases, such as acute myeloid leukemia, increase in prevalence with age, and also why elderly people tend to be more vulnerable to infections such as colds...

2011-08-15 12:19:46

Like fine chefs, scientists are seemingly approaching a day when they will be able to make nearly any type of tissue from human embryonic stem cells. You need nerves or pancreas, bone or skin? With the right combination of growth factors, skill and patience, a laboratory tissue culture dish promises to yield therapeutic wonders. But within these batches of newly generated cells lurks a big potential problem: Any remaining embryonic stem cells - those that haven't differentiated into the...

2010-07-02 19:26:45

Leading stem cell researchers from institutions around the world are issuing warnings about unproven stem cell therapies being marketed on the Internet and have launched a website to educate and protect patients seeking such treatments. Often conducted outside of the United States, most of these therapies have little or no benefit "” and can be dangerous as well as costly. "Many people are going into the hands of predators," said Irving Weissman, MD, director of the Stanford Institute...

2010-06-17 14:38:00

SAN FRANCISCO, June 17 /PRNewswire/ -- The New York Stem Cell Foundation (NYSCF), which has supported more than 23 outstanding young stem cell scientists through its Post-Doctoral Fellowship Program, today announced a significant expansion of its efforts to cultivate the next generation of stem cell scientists by providing $24.5 million in funding to 17 Investigators to launch their own laboratories, train other scientists, and foster innovative high-risk/high-reward research to explore...

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2010-02-22 10:55:00

A top US scientist is making accusations that clinics that offer to "bank" stem cells from the umbilical cords of newborns for use later in life in the event of illness are frauds. Many countries have clinics that allow parents to make a deposit from their neonate's umbilical cord that supposedly will allow their child to have some form of security later in life when the risk of major illnesses occur. In Thailand, parents pay the equivalent of 3,600 US dollars to have clinics deposit stem...

2009-08-03 19:20:29

Researchers at Stanford's School of Medicine have identified the first human bladder cancer stem cell and revealed how it works to escape the body's natural defenses."This is first time we've found this 'don't eat me signal' in a stem cell of a solid cancer," said Irving Weissman, MD, the Virginia & D.K. Ludwig Professor for Clinical Investigation in Cancer Research at the medical school. "We're now moving as fast as we can to look at other tumors to see if this is a universal strategy of...

2009-07-23 11:46:37

Human leukemia stem cells escape detection by co-opting a protective molecular badge used by normal blood stem cells to migrate safely within the body, according to a pair of studies by researchers at Stanford University Medical School."We call it the 'Don't eat me signal,'" said Ravindra Majeti, MD, PhD, assistant professor of hematology at the medical school and the co-first author of one of the studies, which focused on acute myeloid leukemia.Patients whose cancer stem cells express higher...

2009-07-23 11:42:35

Two new studies reveal a way to increase the body's appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting a protein on the surface of those cells that sends a "don't eat me" signal to the macrophage immune cells that serve as a first line of defense, according to the reports in the July 24th issue of the journal Cell, a Cell Press publication.In essence, says Irving Weissman of...

2009-02-11 09:49:48

U.S. medical researchers say they have completed the first genome-wide expression analysis involving leukemia. University of Rochester and Stanford University scientists compared highly enriched normal blood stem cells and leukemic stem cells, identifying several new pathways having a key role in cancer development. The researchers said some scientists believe the best way to eradicate cancer is to find therapies that target cancer's stem cells, but most cancer treatments today fail to attack...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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