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Latest Ischemia Stories

2012-02-08 06:39:03

(Ivanhoe Newswire) -- A recent study suggests that a new scoring method, called the DRAGON score, can help doctors determine quickly who will respond well to the drug alteplase, a clot-busting drug for stroke patients. “The DRAGON score is simple and fast to perform, it has no cost, and it consists solely of factors that are known when the patient is admitted to the hospital or soon after. We found that we could determine the score in less than a minute. This can help the doctor, the...

2012-02-06 10:37:38

A genetic variant that increases the risk of a common type of stroke has been identified by scientists in a study published online in Nature Genetics today. This is one of the few genetic variants to date to be associated with risk of stroke and the discovery opens up new possibilities for treatment. Stroke is the second leading cause of death worldwide (more than one in 10 of all deaths, and over six million deaths annually), and also in developed countries is a major cause of chronic...

2012-02-01 14:32:19

Source of damage to donor organs identified For patients with incurable pulmonary conditions, a lung transplantation is the only available treatment option. However, suitable donor organs are scarce, and even getting them to prospective recipients is not easy. As Professor Alexander Dietrich of the Walther Straub Institute of Pharmacology and Toxicology at LMU explains, “An isolated lung which is no longer perfused with blood can become so severely damaged that it is no longer...

2011-12-28 07:51:30

For patients admitted to an emergency department with chest pain, use of a contemporary or highly sensitive test for levels of troponin I (a protein in muscle tissue) may help rule-out a diagnosis of heart attack, while changes in the measured levels of this biomarker at 3 hours after admission may be useful to confirm a diagnosis of heart attack, according to a study in the December 28 issue of JAMA. One of the most common reasons patients seek care in an emergency department is for acute...

2011-12-01 01:12:17

The ambivalent role of the CXCL12/ CXCR4 axis in heart repair The chemokine CXCL12 acts as a chemical signal which mobilizes hematopoietic and other types of stem cells to leave the bone marrow and enter the circulation. Secretion of CXCL12 also guides these cells to sites at which the perfusion of tissue is sub-optimal due to localized obstruction of blood flow. These capabilities have made CXCL12 and its cognate receptor CXCR4 interesting candidates for therapies aimed at mitigating the...

Damage From Heart Attack Dependent On Time Of Day
2011-11-22 06:20:41

In a first of its kind study, researchers have discovered  that the size of a heart attack and the remaining left-ventricular function that follows depends on the time of day that ischemia in the heart occurs. They found the greatest amount of damage happens when a heart attack occurs between 1:00 am and 5:00 am. Researchers had previously discovered that the amount of tissue death and the return of the blood supply to the heart exhibited a circadian dependence in rats. It was unknown...

2011-11-18 02:52:23

Reducing a protein called Siah2 in mice improves mitochondrial response to low oxygen, a condition cells experience when blood flow is restricted during a heart attack Mitochondria are often called cellular "powerhouses" because they convert nutrients into energy. But these tiny structures also help determine cellular lifespan. Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) are now discovering how mitochondria alternate between duplicating and fragmenting and...


Word of the Day
ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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