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Latest Islets of Langerhans Stories

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2010-06-29 10:42:26

No immune suppression drugs needed In a step toward curing diabetes in humans, scientists at Washington University School of Medicine in St. Louis have alleviated the disease in rats using transplants from both embryonic and adult pigs. The rats adopted the pig transplants as their own and produced enough insulin to control their blood sugar "“ all without the need for anti-rejection drugs. The researchers report their findings online in the American Journal of Pathology. Using a...

2010-06-29 02:28:21

The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the mother's diet early in pregnancy, according to new findings of an international team led by researchers at UCSF. The surprise discovery could lead to simple dietary solutions and possible therapeutics for the disorder known as gestational diabetes, which if untreated, has serious implications for...

2010-06-20 08:47:34

Study shows direct link between circadian clock in pancreas and diabetes The pancreas has its own molecular clock. Now, for the first time, a Northwestern University study has shown this ancient circadian clock regulates the production of insulin. If the clock is faulty, the result is diabetes. The researchers show that insulin-secreting islet cells in the pancreas, called beta-cells, have their own dedicated clock. The clock governs the rhythmic behavior of proteins and genes involved in...

2010-06-15 00:36:19

Insulin-producing beta cells can proliferate in patients recently diagnosed with type 1 diabetes Researchers from the Peninsula Medical School, working in collaboration with colleagues from Glasgow Royal Infirmary and the University of Brighton, have used a unique collection of pancreas specimens taken from patients who died soon after diagnosis of type 1 diabetes to show that they respond to the ongoing process of destruction by inducing their islet cells to proliferate. The research is...

2010-06-04 13:34:43

A team of researchers from several collaborating Baylor University research centers and from Japan's Okayama Graduate School of Medicine have found a way to more consistently isolate pancreatic islet cells from brain dead donors using ductal injection (DI), a process that immediately cools donor islet cells at the injection site. The more successful islet isolation process resulted in the three type 1-diabetes patients, who received islet cell transplants, becoming insulin independent. Their...

2010-02-24 16:16:00

Bee Gee Barry Gibb and wife, Linda, announce American citizenship HOLLYWOOD, Fla., Feb. 24 /PRNewswire-USNewswire/ -- Three months ago, U.S. Senior Airman Tre F. Porfirio was critically wounded after being struck from behind by three high velocity bullets while serving in Afghanistan. On February 13, Porfirio made an extraordinary trip from Washington, D.C., to Miami to appear before an awestruck crowd of 600 at the Love and Hope Ball benefiting the Diabetes Research Institute (DRI) -- the...

2010-01-22 13:18:52

The neuropeptide corticotropin-releasing factor (CRF) makes cameo appearances throughout the body, but its leading role is as the opening act in the stress response, jump-starting the process along the hypothalamus-pituitary-adrenal (HPA) axis. Researchers at the Salk Institute for Biological Studies have found that CRF also plays a part in the pancreas, where it increases insulin secretion and promotes the division of the insulin-producing beta cells. These findings, which will be published...

2009-12-17 17:50:00

MELBOURNE, Australia, Dec. 17 /PRNewswire-FirstCall/ -- Treatment for Diabetic Patients a Major New Objective Key points: *Single injection of proprietary adult stem cells resulted in increased blood insulin levels and sustained reduction in blood glucose levels *Stem cell treatment induced two-fold increase in total numbers of pancreatic islets, and increase in insulin-producing beta cells *Results indicate pancreas may successfully be regenerated by proprietary adult stem cells...

2009-12-15 14:30:00

WASHINGTON, Dec. 15 /PRNewswire-USNewswire/ -- A 21-year old Airman severely wounded in Afghanistan is recovering at Walter Reed Army Medical Center after several surgeries and an unprecedented transplant. The procedure performed by medical teams at Walter Reed and the University of Miami's Miller School of Medicine, is the first known case of successful isolation and transplantation of insulin producing cells following severe trauma requiring complete removal of the pancreas. When...

2009-11-09 07:00:00

GORDONSVILLE, Va., Nov. 9 /PRNewswire/ -- Beta-Pro LLC, a biotechnology firm that provides diabetes researchers with custom cellular and consulting services, has entered a new phase of growth as it bridges the widening gap between an inconsistent, low quality supply of human pancreatic islets and skyrocketing demand. Beta-Pro provides pharmaceutical researchers with a high quality, consistent supply of islets and other biomaterials. The firm isolates and distributes insulin-producing human...