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Last updated on April 25, 2014 at 1:22 EDT

Latest Islets of Langerhans Stories

2009-10-08 11:00:00

St. Jude Children's Research Hospital study results suggest new approaches for preventing disease MEMPHIS, Tenn., Oct. 8 /PRNewswire-USNewswire/ -- St. Jude Children's Research Hospital investigators have discovered how destructive immune cells gain access to insulin-producing cells and help cause diabetes. The finding points to possible new strategies to halt or prevent type I diabetes. Working in mice, researchers demonstrated that to enter key areas of the pancreas known as the...

2009-09-10 15:04:00

MINNEAPOLIS, Sept. 10 /PRNewswire/ -- Exsulin Corporation today announced the start of a phase II human clinical trial of Exsulin(TM), a peptide drug product aimed at restoring insulin production in people with diabetes mellitus. The randomized, controlled 12-week trial in patients with established Type 1 diabetes (T1DM) will be co-led by Mayo Clinic in Rochester, Minn., and McGill University Health Centre in Montreal, Canada. First results are expected to be available in Q2 2010. The...

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2009-07-10 11:55:00

For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, to no avail. Now, they may be one step closer. A protein, whose role in pancreatic development has long been recognized, has been discovered to play an additional and previously unknown regulatory role in the development of cells in the immature endocrine system. These cells ultimately give rise to pancreatic islet cells, which include beta cells.By carefully defining the...

2009-06-26 11:29:00

MINNEAPOLIS, June 26 /PRNewswire-USNewswire/ -- Receiving more than $80,000 from Minnesota and Wisconsin Multiple District Lions Clubs over the past years, Spring Point Project, a non profit organization developing pig donors for pancreatic islet transplantation to cure diabetes, is attending the Lions Clubs International 92nd Convention. Over 12,000 Lions delegates from more than 200 countries are expected to attend the convention July 6-10, 2009, in Minneapolis, Minn. Spring Point Project...

2009-04-10 08:36:09

Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE). The study, which suggests a new approach to treating Type 1 diabetes, was published online on April 8 in the journal Transplantation.The team of scientists showed that after transplantation, the...

2009-03-16 15:57:37

More than five years ago, Dr. Lawrence C.B. Chan and colleagues in his Baylor College of Medicine laboratory cured mice with type 1 diabetes by using a gene to induce liver cells to make insulin. "Now we know how it works," said Chan, director of the federally designed Diabetes and Endocrinology Research Center at BCM and chief of the division of endocrinology in BCM's department of medicine. "The answer is adult stem cells." A gene called neurogenin3 proved critical to inducing cells in the...

2009-02-13 15:05:00

Cutting-edge DNA testing technology provided by GeneSeek Inc. LINCOLN, Neb., Feb. 13 /PRNewswire/ -- A privately held biotechnology company, will be used for medical-grade source pigs which are being developed by Spring Point Project, a Minnesota non-profit organization providing pig islet cells for transplantation to cure diabetes. With this technology, GeneSeek, a certified Illumina CSPro laboratory and global leader in contractual high-throughput genotyping, will help Spring Point Project...

2009-01-27 12:00:00

WYNNEWOOD, Pa., Jan. 27 /PRNewswire/ -- A study released today in Endocrine Practice (2008;14:1075), the leading peer-reviewed journal for practicing endocrinologists in the US and 65 countries, reports a ground breaking discovery with the potential to reverse type 1 and 2 diabetes. Scientists at CureDM, Inc. have identified a 14- amino acid human peptide, Human proIslet Peptide (HIP), consisting of the bioactive region in the human REG3a gene responsible for regenerating pancreatic...

2009-01-22 08:41:24

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s. In recent years, research has focused on the anatomical sites best suited for hosting transplanted islet cells. Experimental sites have included the spleen, liver, peritoneal cavity, omentum, subcutaneous tissues and gastric submucosa. However, many transplant attempts at a variety of anatomical sites have failed because of a variety of...

2009-01-16 10:53:01

Researchers at the University of Pittsburgh School of Medicine, funded by JDRF, have discovered that adult beta cells have the ability to replicate with the help of a protein known as cdk6. This research was led by Andrew F. Stewart, M.D., a Professor of Medicine and Chief of the Division of Endocrinology and Metabolism at the University of Pittsburgh School of Medicine. The complete findings of this discovery can be found in the early online version of Diabetes."Most scientists thought that...