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Latest Islets of Langerhans Stories

2009-03-16 15:57:37

More than five years ago, Dr. Lawrence C.B. Chan and colleagues in his Baylor College of Medicine laboratory cured mice with type 1 diabetes by using a gene to induce liver cells to make insulin. "Now we know how it works," said Chan, director of the federally designed Diabetes and Endocrinology Research Center at BCM and chief of the division of endocrinology in BCM's department of medicine. "The answer is adult stem cells." A gene called neurogenin3 proved critical to inducing cells in the...

2009-02-13 15:05:00

Cutting-edge DNA testing technology provided by GeneSeek Inc. LINCOLN, Neb., Feb. 13 /PRNewswire/ -- A privately held biotechnology company, will be used for medical-grade source pigs which are being developed by Spring Point Project, a Minnesota non-profit organization providing pig islet cells for transplantation to cure diabetes. With this technology, GeneSeek, a certified Illumina CSPro laboratory and global leader in contractual high-throughput genotyping, will help Spring Point Project...

2009-01-27 12:00:00

WYNNEWOOD, Pa., Jan. 27 /PRNewswire/ -- A study released today in Endocrine Practice (2008;14:1075), the leading peer-reviewed journal for practicing endocrinologists in the US and 65 countries, reports a ground breaking discovery with the potential to reverse type 1 and 2 diabetes. Scientists at CureDM, Inc. have identified a 14- amino acid human peptide, Human proIslet Peptide (HIP), consisting of the bioactive region in the human REG3a gene responsible for regenerating pancreatic...

2009-01-22 08:41:24

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s. In recent years, research has focused on the anatomical sites best suited for hosting transplanted islet cells. Experimental sites have included the spleen, liver, peritoneal cavity, omentum, subcutaneous tissues and gastric submucosa. However, many transplant attempts at a variety of anatomical sites have failed because of a variety of...

2009-01-16 10:53:01

Researchers at the University of Pittsburgh School of Medicine, funded by JDRF, have discovered that adult beta cells have the ability to replicate with the help of a protein known as cdk6. This research was led by Andrew F. Stewart, M.D., a Professor of Medicine and Chief of the Division of Endocrinology and Metabolism at the University of Pittsburgh School of Medicine. The complete findings of this discovery can be found in the early online version of Diabetes."Most scientists thought that...

2008-12-11 11:30:00

MINNEAPOLIS and ST. PAUL, Minn., Dec. 11 /PRNewswire/ -- The University of Minnesota has received a $40 million pledge for diabetes research from the Richard M. Schulze Family Foundation. Goals for the funding, to be paid over five years, are to capitalize on the University's strength in diabetes research and to accelerate the timeline to translate it into a viable cure for people with type 1 diabetes. The gift is the second largest in the history of the University and the second...

2008-11-20 20:06:56

Doctors have tricked mouse immune systems into thinking cells from a donor pancreas are theirs, bringing hope to diabetes patients, U.S. researchers said. The new technique, to fight type 1 diabetes, eliminated the need for drugs that inhibit immune-system activity in diabetic mice that had insulin-producing islet cell transplantation, Northwestern University Feinberg School of Medicine researchers said. Immunosuppressive drugs prevent bodies from rejecting the islet cells, but they're toxic...

2008-11-10 18:00:00

SAN DIEGO, Nov. 10, 2008 (GLOBE NEWSWIRE) -- MicroIslet Inc. (OTCBB:MIIS) (http://www.microislet.com), a biotechnology company engaged in the development and commercialization of cell therapies for diabetes, today announced that it filed a voluntary petition for reorganization under Chapter 11 of the U.S. Bankruptcy Code. The company plans to continue operating the business without interruption as management focuses on developing and executing on a corporate restructuring plan. "During the...

2008-10-30 09:00:11

Bayhill Therapeutics, Inc., a leading developer of therapies for autoimmune diseases, and the Juvenile Diabetes Research Foundation, the world's leading charitable funder of type 1 diabetes research, today announced a partnership to support Bayhill's ongoing Phase I/II human clinical trial of BHT-3021, a DNA vaccine to reverse the immune response that causes type 1 diabetes. BHT-3021 is an antigen-specific immunotherapeutic DNA vaccine designed to reverse the underlying autoimmune...

2008-10-28 09:00:07

Geron Corporation (Nasdaq:GERN) today announced the publication of data showing the successful engraftment of human embryonic stem cell (hESC)-derived pancreatic islet-like clusters (ILCs) in diabetic mice. After transplantation, the ILCs continued to express important pancreatic islet proteins, responded to high levels of glucose in the blood, and extended the survival of recipient animals. Pancreatic islet cells normally secrete insulin in response to high levels of glucose in the...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'