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2009-05-20 07:20:00

New estimates of the likelihood that a latent case of tuberculosis (TB) will become active have resulted in a roughly 50 percent increase over previous estimates of the number of people needed to be screened (NNS) to prevent an active infection, limiting the cost effectiveness of screening in many Center for Disease Control and Prevention (CDC)-defined risk groups, according to an analysis conducted by experts in the epidemiology of the disease. The research will be presented at the American...

2009-03-31 14:21:42

British medical scientists say the discovery of a large number of slow-growing Mycobacterium tuberculosis bacteria might lead to new anti-TB drugs. Until now it was thought that M. tuberculosis bacteria in the lungs of TB patients were rapidly multiplying. However recent research by Simon Waddell and colleagues from St George's University of London and the University of Leicester revealed the tuberculosis bacteria in the sputum of TB patients resemble bacteria that are growing very slowly or...

2009-03-24 06:00:00

SUNNYVALE, Calif.March 24 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD) today announced details of technology expected to revolutionize the speed of diagnosis of Mycobacterium tuberculosis (TB) and the resistance to common drug treatment for the disease. The new test technology, developed in partnership with Foundation for Innovative New Diagnostics (FIND) and the University of Medicine and Dentistry of New Jersey (UMDNJ), and funded by the National Institute of Allergy &...

2009-03-19 11:18:58

The U.S. tuberculosis rate fell to an all-time low of 4.2 cases per 100,000 people, or 12,898 new cases, in 2008, federal health officials said. However, the Centers for Disease Control and Prevention's Mortality and Morbidity Weekly Report said progress in eliminating TB hit a plateau in recent years, with a 3.8 percent average annual rate of decline for 2000-2008, compared to 7.3 percent for 1993-2000. TB continued to disproportionately affect racial and ethnic minorities and foreign-born...

2009-01-23 14:36:31

A four-month treatment with the drug rifampin is better tolerated for tuberculosis than the nine-month treatment of isoniazid, Canadian researchers said. Dr. Dick Menzies of the McGill University said patients who are infected with the latent form of TB show no symptoms and are not contagious, yet they pose the biggest challenge when it comes to controlling the disease. Patients who currently receive a diagnosis of latent TB are treated for nine months with daily doses of isoniazid;...

2009-01-22 14:36:12

MUHC researchers are studying a shorter treatment with fewer side effects Patients who are infected with the latent form of tuberculosis (TB) show no symptoms and are not contagious, yet they pose the biggest challenge when it comes to controlling the disease. The latest study by Dr. Dick Menzies of the Research Institute of the McGill University Health Centre (MUHC) describes a new potential treatment for this particular form of TB. The paper based on this study was recently published in the...

2008-09-19 17:02:55

The skeleton of a man discovered in a shallow grave on what is now a college campus in England could belong to one of Britain's earliest victims of tuberculosis. Radiocarbon dating suggests the man died in the fourth century, around A.D. 302, when Romans ruled the region. He was interred in a shallow scoop in a flexed position, on his right side. The man, aged 26 to 35 years old, suffered from iron deficiency anemia during childhood and at 5-foot, 4-inches, was shorter than average for...

2008-09-15 09:00:11

Tuberculosis drug shows promise against latent bacteria WASHINGTON, Sept. 12 (Xinhua) -- A new study has shown that an investigational drug R207910, currently in clinical trials against multi-drug resistant tuberculosis strains, is quite effective at killing latent bacteria, a report said on Friday. This revelation suggests that R207910 may lead to improved and shortened treatments for this globally prevalent disease, researchers from Johnson & Johnson reported in the Sept. 12 issue...

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2008-08-25 10:55:00

Aggressive treatment involving a combination of drugs may be the cure for extensively drug-resistant tuberculosis, researchers report.Writing in The Lancet, researchers found that despite fears of being untreatable, TB could be cured with a combination of at least five drugs.Multi-drug resistant (MDR) TB is resistant to the most commonly used treatments isoniazid and rifampin.However, these treatments are ineffective when used to battle extremely resistant (XDR) TB.The recent study consisted...

2008-07-23 21:00:14

Tuberculosis occurs most often in the United States in residents born in sub-Saharan Africa and Southeast Asia, researchers say. Dr. Kevin P. Cain of the Centers for Disease Control and Prevention in Atlanta examined the 46,970 cases of TB disease reported from 2001 to 2006 among foreign-born people in the United States. The study, published in the Journal of the American Medical Association, found 12,928 cases, or 28 percent, were among those in the United States less than two years....


Latest Isoniazid Reference Libraries

72_0ab04c9452ae9b3c6ae51f6deb1bcc35
2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

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Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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