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Latest IT-101 Stories

2012-06-22 06:14:58

(Ivanhoe Newswire) — There are more than 42 thousand new diagnosed cases of pancreatic cancer in the U.S., and of those, more than 35 thousand have resulted in death. Now researchers are looking at a new treatment that could change how we view pancreatic cancer. A novel chemotherapeutic agent, the highly selective MEK1/2 inhibitor BAY 86-9766, may be a promising future treatment for pancreatic ductal adenocarcinoma (PDAC). In a preclinical therapeutic study, BAY 86-9766 was evaluated...

2011-01-19 16:00:00

PITTSBURGH, Jan. 19, 2011 /PRNewswire/ -- Precision Therapeutics, Inc. will present pancreatic cancer data based on Precision's ChemoFx® in-vitro chemosensitivity test at the 2011 American Society of Clinical Oncology (ASCO) GI Symposium, January 20-22 in San Francisco, California. The two studies accepted by the ASCO GI are titled, InVitro Sensitivity of 5 FU and Gemcitabine in Pancreatic Cancer and Pattern of In Vitro Chemotherapy Response in Pancreatic Cancer and...

2010-09-15 07:00:00

LONDON and NEW YORK, Sept. 15 /PRNewswire/ -- Spirogen Limited (the "Company") and Celtic Therapeutics Holdings LP ("Celtic Therapeutics") announced today the commencement of a Phase II clinical trial of SG2000 in ovarian cancer. The trial is being sponsored by the National Cancer Institute (NCI) of the USA, and is now actively recruiting patients for treatment. The open-label Phase II study will evaluate the overall response rate of SG2000 in approximately 50 patients with recurrent,...

2008-11-03 09:00:40

Calando Pharmaceuticals, Inc., a majority-owned subsidiary of Arrowhead Research Corporation (NASDAQ:ARWR), announced today that its CEO, Dr. James Hamilton, will present at the 19th Annual Oppenheimer Healthcare Conference on Tuesday, November 4, 2008 at 11:00am ET. The conference is being held at the Waldorf Astoria Hotel in New York City. Dr. Hamilton's presentation will discuss Calando's proprietary delivery systems for siRNA and small molecule drugs and Calando's clinical program for its...

2008-10-24 09:00:07

Calando Pharmaceuticals, a majority-owned subsidiary of Arrowhead Research, has completed the IT-101 Phase I clinical study conducted at City of Hope in Duarte, California. The company expects the entire study data to be published in early 2009. IT-101 is an experimental, nanoparticle therapeutic that consists of the drug camptothecin conjugated to a cyclodextrin polymer. IT-101, the first drug candidate in Calando's proprietary Cyclosert pipeline, has now successfully completed a Phase I...

2008-10-23 09:00:10

Calando Pharmaceuticals, a majority-owned subsidiary of Arrowhead Research Corporation (NASDAQ:ARWR), announced today completion of the IT-101 Phase I clinical study conducted at City of Hope in Duarte, California. The company expects the entire study data to be published in early 2009. IT-101 is an experimental, nanoparticle therapeutic that consists of the drug camptothecin (CPT) conjugated to a cyclodextrin polymer. IT-101, the first drug candidate in Calando's proprietary Cyclosert(TM)...

2008-10-21 09:00:12

Arrowhead Research Corporation (NASDAQ: ARWR) announced today that the Company's CEO has provided an update letter to stockholders on its majority owned subsidiary, Calando Pharmaceuticals: Dear Arrowhead Stockholders, Calando Pharmaceuticals is Arrowhead's most mature biopharmaceutical subsidiary. Based on technology developed at the California Institute of Technology, Calando's proprietary linear cyclodextrin nanoparticle technology has been optimized to deliver small molecule...

2008-09-15 09:00:58

Calando Pharmaceuticals, a majority-owned subsidiary of Arrowhead Research Corporation (NASDAQ:ARWR), announced today that pre-clinical development of a second siRNA oncology therapeutic, CALAA-02, is underway. The intracellular target for CALAA-02 is HIF-2alpha, or Hypoxia Inducible Factor-2 alpha. HIF-2alpha is overexpressed in a number of solid tumors and is critical for many aspects of tumorigenesis, such as metastasis, angiogenesis, tumor cell proliferation, and tumor response to...

2008-09-12 09:00:09

Calando Pharmaceuticals, a majority owned subsidiary of Arrowhead Research, has started a Phase II clinical trial in the US evaluating the safety and efficacy of its drug candidate, IT-101, in patients with platinum-sensitive ovarian cancer. The study is open for enrollment. This Phase II study is designed to determine if IT-101 treatment initiated after a standard second line course of platinum chemotherapy in patients who have stable disease, a partial response or a complete response can...

2008-09-11 09:00:48

Calando Pharmaceuticals, Inc., a majority owned subsidiary of Arrowhead Research Corporation (NASDAQ:ARWR), announced today that it has initiated a Phase II clinical trial in the United States evaluating the safety and efficacy of its drug candidate, IT-101 in patients with platinum-sensitive ovarian cancer. The study is open for enrollment. Previous work with IT-101 suggests that twice monthly "maintenance doses" of IT-101 given after the patient's standard chemotherapy may have minimal...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.