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Last updated on April 18, 2014 at 9:47 EDT

Latest John Dick Stories

2014-02-13 10:35:34

Cancer researchers led by stem cell scientist Dr. John Dick have discovered a pre-leukemic stem cell that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia (AML). The research, published online today in Nature is a significant leap in understanding the steps that a normal cell has to go through as it turns into AML, says Dr. Dick, and sets the stage to advance personalized cancer medicine by...

2013-12-02 09:57:42

Scientists and surgeons at Princess Margaret Cancer Centre have discovered a promising new approach to treating colorectal cancer by disarming the gene that drives self-renewal in stem cells that are the root cause of disease, resistance to treatment and relapse. Colorectal cancer is the third leading cause of cancer-related death in the Western world. "This is the first step toward clinically applying the principles of cancer stem cell biology to control cancer growth and advance the...

2012-12-14 15:05:36

Shed light on resistance to treatment Cancer scientists led by Dr. John Dick at the Princess Margaret Cancer Centre have found a way to follow single tumor cells and observe their growth over time. By using special immune-deficient mice to propagate human colorectal cancer, they found that genetic mutations, regarded by many as the chief suspect driving cancer growth, are only one piece of the puzzle. The team discovered that biological factors and cell behaviour — not only genes...

2011-08-29 12:10:19

Paving the way for personalized treatment Cancer scientists have long debated whether all cells within a tumour are equal or whether some cancer cells are more potent - a question that has been highly investigated in experimental models in the last decade. Research published today in Nature Medicine (10.1038/nm.2415) focuses on patients and shows that acute myeloid leukemia (AML) contains rare cells with stem cell properties, called leukemia stem cells (LSC), that are better at predicting...

2011-04-27 09:36:00

To view the Social Media Release, click here: http://smr.newswire.ca/en/canadian-cancer-society/when-cancer-strikes-the-most-vulnerable TORONTO, April 27 /PRNewswire/ - A new Canadian Cancer Society-funded study will investigate the genetic puzzle of a devastating nervous system cancer that strikes infants, and identify potential new treatments for the disease. The study is one of 52 new research projects worth more than $21 million announced today by the Society. The projects cover...

2009-07-06 11:39:38

 Dr. John Dick, Senior Scientist at the Ontario Cancer Institute, the research arm of Princess Margaret Hospital, co-led a multinational team that has developed the first leukemia therapy that targets a protein, CD123, on the surface of cancer stem cells that drive acute myeloid leukemia (AML), which is an aggressive disease with a poor outcome.Dr. Richard Lock is leading the clinical trial in Australia that expands on research suggesting that antibodies targeting cancer stem cells...

2008-06-18 18:00:42

By Sheryl Ubelacker, Health Reporter, THE CANADIAN PRESS TORONTO - The federal government is investing more than $100 million into cancer stem cell research in partnership with California, Health Minister Tony Clement said Wednesday. In an announcement at the BIO 2008 International Convention in San Diego, Clement said the money will go to the Cancer Stem Cell Consortium, which will work with the California Institute for Regenerative Medicine with the goal of understanding how to prevent...