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Latest John M. Maris Stories

2013-01-21 10:27:56

CHOP researcher leads large multicenter gene sequencing study of neuroblastoma An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations–mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to...

2010-12-01 22:50:58

At same gene site, variants may predispose to cancer and also drive disease progression Pediatric cancer researchers have identified variations in a gene as important contributors to neuroblastoma, the most common solid cancer of early childhood. The study team, led by researchers at The Children's Hospital of Philadelphia, found that common variants in the LMO1 gene increase the risk of developing an aggressive form of neuroblastoma, and also mark the gene for continuing to drive the...

2010-09-30 17:09:23

New standard of care in high-risk neuroblastoma seen in immunotherapy results Using immunotherapy"”biologic agents that stimulate the body's immune system"”pediatric oncologists have achieved the first substantial increase in over a decade in cure rates for the childhood cancer neuroblastoma. A newly released study shows that the new treatment improved two-year survival rates by 20 percent, compared to standard treatment for an aggressive form of neuroblastoma, a cancer of the...

2010-09-29 16:07:00

-- New Standard of Care in High-Risk Neuroblastoma Seen in Immunotherapy Results-- PHILADELPHIA, Sept. 29 /PRNewswire-USNewswire/ -- Using immunotherapy--biologic agents that stimulate the body's immune system--pediatric oncologists have achieved the first substantial increase in over a decade in cure rates for the childhood cancer neuroblastoma. A newly released study shows that the new treatment improved survival rates by 20 percent, compared to standard treatment for an aggressive form...

2010-06-15 00:59:03

CHOP oncology chief working to translate his lab's genetic findings into treatments Pediatric oncologist John M. Maris, M.D., describes the current state of the science in combating neuroblastoma, the most common solid cancer of early childhood. In his article in the June 10, 2010 New England Journal of Medicine, "Recent Advances in Neuroblastoma," Maris reviews the field's latest research knowledge"”much of it based on efforts by Maris and his colleagues at The Children's Hospital of...

2010-06-14 10:25:00

--CHOP Oncology Chief Working to Translate His Lab's Genetic Findings into Treatments-- PHILADELPHIA, June 14 /PRNewswire-USNewswire/ -- Pediatric oncologist John M. Maris, M.D., describes the current state of the science in combating neuroblastoma, the most common solid cancer of early childhood. In his article in the June 10, 2010 New England Journal of Medicine, "Recent Advances in Neuroblastoma," Maris reviews the field's latest research knowledge--much of it based on efforts by Maris...

2009-06-22 11:39:00

--Whole-Genome Searches Are Revealing Secrets of a Childhood Cancer-- PHILADELPHIA, June 22 /PRNewswire-USNewswire/ -- Two new studies from The Children's Hospital of Philadelphia advance the search for genetic events that result in neuroblastoma, a puzzling, often-deadly type of childhood cancer. Originating in the peripheral nervous system, neuroblastoma is the most common solid cancer of early childhood and causes 15 percent of all childhood cancer deaths. "Only two years ago we had...

2009-06-22 09:36:00

- In a First, Immunotherapy Works Against Neuroblastoma - PHILADELPHIA, June 22 /PRNewswire-USNewswire/ -- A multicenter research team has announced encouraging results for an experimental therapy using elements of the body's immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the nervous system. John M. Maris, M.D., chief of Oncology at The Children's Hospital of Philadelphia, co-authored the phase 3 clinical trial, which was led by Alice Yu, M.D.,...

2009-06-22 07:33:10

Two new studies from The Children's Hospital of Philadelphia advance the search for genetic events that result in neuroblastoma, a puzzling, often deadly type of childhood cancer. Originating in the peripheral nervous system, neuroblastoma is the most common solid cancer of early childhood and causes 15 percent of all childhood cancer deaths. "Only two years ago we had very little idea of what causes neuroblastoma," study leader John M. Maris, M.D., chief of Oncology and director of the...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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