Latest Joseph Garner Stories
Nine out of 10 drugs successfully tested in mice and other animal models ultimately fail to work in people, and one reason may be traced back to a common fact of life for laboratory mice: they're cold.
For decades, the traditional practice in animal testing has been standardization, but a study involving Purdue University has shown that adding as few as two controlled environmental variables to preclinical mice tests can greatly reduce costly false positives, the number of animals needed for testing and the cost of pharmaceutical trials.
Mice raised in cages may relieve stress with behaviors more often associated with mice living in the wild, Purdue University in Indiana reports. For researchers, this finding may mean they have to give up some control and allow mice to express themselves more naturally to ensure more reliable research data, the West Lafayette, Ind., university said in a news release. Laboratory mice live in sterile environments controlled by humans, which can create stress for the animals since they don't...
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