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Latest Joseph Takahashi Stories

2014-04-29 12:34:38

DALLAS, April 29, 2014 /PRNewswire-USNewswire/ -- The National Academy of Sciences (NAS) today announced the election of Dr. Zhijian "James" Chen, professor of molecular biology, who holds the George L. MacGregor Distinguished Chair in Biomedical Science and is also a Howard Hughes Medical Institute investigator at UT Southwestern Medical Center. http://photos.prnewswire.com/prnvar/20140429/81899 Being elected to the NAS is one of the highest honors in American science, and with Dr....

2014-04-16 10:13:27

All organisms, from mammals to fungi, have daily cycles controlled by a tightly regulated internal clock, called the circadian clock. The whole-body circadian clock, influenced by the exposure to light, dictates the wake-sleep cycle. At the cellular level, the clock is controlled by a complex network of genes and proteins that switch each other on and off based on cues from their environment. Most genes involved in the regulation of the circadian clock have been characterized, but Akihiro...

2014-01-15 14:20:42

Researchers at the University of Cincinnati (UC) have identified key molecular components linking circadian rhythms and cell division cycles in Neurospora crassa, providing insights that could lead to improved disease treatments and drug delivery. The researchers in the UC College of Medicine Department of Molecular and Cellular Physiology, led by Christian Hong, PhD, published their findings Monday, Jan. 13, online ahead of print in PNAS (Proceedings of the National Academy of Sciences)....

Discovery May Accelerate Body's Response To Infection And Autoimmune Disorders
2013-11-08 08:57:46

University of Texas Southwestern Medical Center UT Southwestern Medical Center researchers report that disrupting the light-dark cycle of mice increased their susceptibility to inflammatory disease, indicating that the production of a key immune cell is controlled by the body’s circadian clock. The study published in the Nov. 8 edition of Science identifies a previously hidden pathway by which the body’s circadian clock controls the numbers of key inflammatory cells called...

How Is Protein Synthesis Controlled In The Brain Clock?
2013-08-22 05:21:41

April Flowers for redOrbit.com - Your Universe Online Many factors keep us from getting a good night’s sleep. Prime culprits include overnight flights across the ocean, graveyard shifts, and stress-induced insomnia. A new study from McGill and Concordia Universities gives hope, however, that these common sleep disturbances may one day be put to bed. The Earth’s rotation is responsible for creating day and night, and the daily rhythms of all living beings. Mammals have a “circadian...

2013-06-19 14:29:34

Gladstone-led study sheds light on molecular basis for metabolic health and disease Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called "circadian clock" are complex, and the molecular processes behind it have long eluded scientists. But now, researchers at the Gladstone Institutes have discovered how one important protein falls under direct instructions from the body's circadian clock....

2010-07-13 15:21:41

Disruption of two genes that control circadian rhythms can lead to diabetes, a researcher at UT Southwestern Medical Center has found in an animal study. Mice with defective copies of the genes, called CLOCK and BMAL1, develop abnormalities in pancreatic cells that eventually render the cells unable to release sufficient amounts of insulin. "These results indicate that disruption of the daily clock may contribute to diabetes by impairing the pancreas' ability to deliver insulin," said Dr....

2009-09-01 09:05:24

Japanese and U.S. scientists say they've identified an enzyme that can be inhibited to extend the circadian 24-hour metabolic cycle to more than 48 hours. The scientists said the circadian clock has long been known to play a central role in regulating the daily activities of living organisms. But its detailed biochemical mechanisms have largely remained unidentified. Researchers at the Riken Center for Developmental Biology in Tokyo, led by Hiroki Ueda and Northwestern University Professor...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'