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Latest JUPITER trial Stories

2010-11-16 21:58:37

Rolling back suggestions from previous studies, a Johns Hopkins study of 950 healthy men and women has shown that taking daily doses of a cholesterol-lowering statin medication to protect coronary arteries and ward off heart attack or stroke may not be needed for everyone. In a study to be presented Nov. 16 at the American Heart Association's (AHA) annual Scientific Sessions in Chicago, the Johns Hopkins team found that nearly 95 percent of all heart attacks, strokes or heart-related deaths...

2010-09-28 20:58:08

Average C-reactive protein (CRP) values vary in diverse populations "” possibly impacting how doctors estimate cardiovascular risk and determine statin treatment, according to a new study in Circulation: Cardiovascular Genetics, a journal of the American Heart Association. CRP is a marker of inflammation, and high levels of it in the blood have been associated with a higher risk for heart disease. But it's uncertain if the association is causal. Statins are a class of...

2010-09-28 13:52:58

A new analysis suggests that broader statin use among adult patients may be a cost-effective way to prevent heart attack and stroke. The Stanford University School of Medicine study also found that using a popular test - a screening for high sensitivity C-reactive protein, or CRP - to identify patients who may benefit from statin therapy would be cost-effective, but only under certain scenarios. "If statins are really as safe and effective as they appear to be, broadening the indications for...

2010-08-10 00:00:00

DUBLIN, Ireland and MYSTIC, Conn., Aug. 10 /PRNewswire-FirstCall/ -- Amarin Corporation plc (Nasdaq: AMRN), a clinical-stage biopharmaceutical company with a focus on cardiovascular disease, today announced that its MARINE trial, a Phase 3 clinical trial of AMR101, has completed patient enrollment and randomization into the treatment phase of this trial. The Company indicated that top line results from this trial are expected early in 2011, towards the early part of the range of guidance...

2010-07-26 13:04:28

The European Society of Cardiology (ESC) is concerned that interpretations of a paper about cholesterol, published in the Lancet (1), could act to deter ongoing research efforts into developing new therapeutic strategies to increase high density lipoprotein (HDL) cholesterol.  Caution, the ESC experts advise, should be displayed in the interpretation of the results. In the Lancet study, Paul Ridker and colleagues, from Brigham and Women's Hospital (Boston, MA, USA), undertook a...

2010-06-30 09:34:05

A meta-analysis of previously published studies finds no evidence that statins are associated with a reduced risk of death among individuals at risk for but with no history of cardiovascular disease, according to a report in the June 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. "Statins are now one of the most widely used drugs for the treatment and prevention of cardiovascular disease both among individuals with established disease and among high-risk healthy...

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2010-06-29 11:00:00

On Monday, researchers said they did not find evidence that cholesterol-reducing drugs can help extend the life of patients at risk of heart disease. The study involved 65,229 people who were questioned about the use of the cholesterol-reducing drugs, also known as statins.  Statins are the world's top-selling prescription drugs.  According to health industry data firm IMC Health, over 238 million prescriptions for cholesterol-lowering drugs were dispensed by retail pharmacies in...

2010-06-24 15:39:33

C-reactive protein (CRP) is used to assess disease activity in diverse inflammatory disorders including inflammatory bowel disease (IBD). However, in IBD, a significant number of patients present with low CRP levels despite clinically active disease. In paediatric patients with IBD the performance of CRP is an understudied area. High-sensitivity CRP (hs-CRP) measures CRP levels that were previously thought to be under the detection limit. In paediatric IBD, this kind of highly sensitive...

2010-06-02 15:11:13

Prognostic markers provide tools for discriminating between groups of patients who are at different risks of a particular outcome, and therefore should help clinicians to manage disease. In a comprehensive overview of studies looking at one such proposed marker, C-reactive protein (CRP) in coronary artery disease, Harry Hemingway and colleagues, from University College London, show that despite the inclusion of many tens of thousands of patients in research on this specific question, the...

2010-05-03 14:54:46

New study finds post-operative statin use decreases the need for revision surgery The use of statins "“ drugs commonly prescribed to help lower cholesterol levels "“ may play an important role in decreasing complications among patients undergoing total hip replacement (THR), according to a study published in the May 2010 issue of The Journal of Bone and Joint Surgery (JBJS). "We found that use of statins substantially reduced the risk of revision after hip replacement surgery,...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.