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Last updated on April 20, 2014 at 17:20 EDT

Latest Juvenile myelomonocytic leukemia Stories

2011-12-10 13:00:00

SAN DIEGO, Dec. 10, 2011 /PRNewswire-USNewswire/ -- Hematopoietic cell transplantation (HCT), the transplantation of blood-forming stem cells from the bone marrow, peripheral blood, or umbilical cord blood, is the primary option for treatment for many patients who suffer from various hematologic disorders, including blood cancers, sickle cell disease, bone marrow deficiencies, bleeding disorders, and autoimmune disorders. Research investigating breakthroughs in hematopoietic cell...

2011-07-01 13:01:47

Researchers at Brigham and Women's Hospital have developed a means of improving prognosis methods and predicting how long patients with MDS will live after diagnosis by identifying certain gene mutations in their abnormal bone marrow For patients with myelodysplastic syndromes (MDS), choosing the appropriate treatment depends heavily on the prognosis. Those patients at the highest risk of dying from their disease are typically offered the most aggressive therapies, while patients at lower...

2011-04-05 08:26:00

(Ivanhoe Newswire) -- An experimental drug lessens symptoms of a rare form of childhood leukemia and offers significant insight into the cellular development of the disease, according to findings from a new UCSF study. The mouse model research could spearhead the development of new leukemia therapies and paves the way for future clinical trials in humans. "Although this drug did not produce a cure, it alleviated the symptoms of leukemia as long as the treatment was continued and delayed the...

2011-03-31 00:46:49

An experimental drug lessens symptoms of a rare form of childhood leukemia and offers significant insight into the cellular development of the disease, according to findings from a new UCSF study. The mouse model research could spearhead the development of new leukemia therapies and paves the way for future clinical trials in humans. "Although this drug did not produce a cure, it alleviated the symptoms of leukemia as long as the treatment was continued and delayed the development of a more...

2011-02-04 00:23:02

For blood cancer patients at high risk of relapse, hematopoietic stem cell transplantation (HSCT), the transplantation of blood-forming stem cells, is one of best options for treatment and a potential cure. Unfortunately, the most common complication of HSCT is graft-versus-host disease (GVHD), a serious and often deadly post-transplant complication that occurs when the newly transplanted donor cells recognize the recipient's own cells as foreign and react by attacking the cells in the...

2010-08-09 14:24:04

A UCSF-led team has discovered a direct link between an inherited genetic mutation, a set of developmental abnormalities and a rare form of childhood leukemia called juvenile myelomonocytic leukemia, or JMML. The study demonstrates a new familial link in JMML and has significant implications, the researchers say, for improving the diagnosis and treatment of the disease. Findings are reported in the August 8, 2010, Advance Online Publication of the journal Nature Genetics, available at...

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2010-01-08 11:56:31

Discovery will enable doctors to accurately diagnose and treat skin rashes in bone marrow transplant patients and personalize GVHD treatment University of Michigan researchers have identified the first biomarker of graft-versus-host disease of the skin. The discovery makes possible a simple blood test that should solve a treatment dilemma facing doctors with patients who frequently develop rashes after bone marrow transplants. The biomarker also makes it possible to predict who is at greatest...

2009-11-05 13:29:55

For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options. All fifty-eight patients, with a median age of 63 and all with advanced acute myeloid leukemia or high-risk myelodysplastic syndrome "“ a pre-leukemic...

2009-09-29 07:55:08

Lab's findings could also be applied to leukemia and solid tumors Van Andel Research Institute (VARI) researchers are one step closer to finding new ways to treat Myelodysplastic Syndrome (MDS), a bone marrow disease that strikes up to 15,000 people each year in the United States, and that sometimes results in acute myeloid leukemia.  Researchers found that the gene RhoB is important to the disease's progression and could prove to be a therapeutic target for late-stage MDS. "Using our...

2009-01-09 16:00:00

National Cord Blood Program Provides Stem Cells NEW YORK, Jan. 9 /PRNewswire-USNewswire/ -- A two year old child from Florida is free of signs of juvenile myelomonocytic leukemia (JMML), a very rare form of pediatric leukemia, seventeen months after receiving a transplant with cord blood from the National Cord Blood Program (NCBP) of the New York Blood Center's Howard P. Milstein National Cord Blood Center. Juvenile myelomonocytic leukemia generally affects children under the age of five...