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Latest Kaposi's sarcoma Stories

2011-12-14 19:44:17

Human tumor viruses contribute to 15-20% of human cancers worldwide. Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma (KS) and two other rare lymphoproliferative malignancies. KS is the most common cancer in HIV-infected untreated individuals and remains a primary cause of cancer deaths in many subequatorial African countries as a result of the AIDS pandemic. Researchers at the Institute of Biotechnology and Research Programs Unit (Genome-Scale Biology) at the...

2011-04-11 22:14:31

The number of cancers and the types of cancers among people living with AIDS in the U.S. have changed dramatically during the 15-year period from 1991-2005, according to an article published online April 11th in the Journal of the National Cancer Institute. It is known that HIV-infected patients face an increased risk of Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer--the AIDS-defining cancers--and that the incidence of these cancers dropped when highly active anti-retroviral...

2011-01-20 22:03:33

Kaposi sarcoma-associated herpesvirus produces a protein that blocks the cell's inflammatory response In a new paper published Jan. 21 in the journal Science, a team of researchers led by Microbiology and Immunology professor Blossom Damania, PhD, has shown for the first time that the Kaposi sarcoma virus has a decoy protein that impedes a key molecule involved in the human immune response. The work was performed in collaboration with W.R. Kenan, Jr. Distinguished Professor, Jenny Ting, PhD....

2010-05-07 10:33:19

Research from the University of Leeds has identified how the virus which causes Kaposi's Sarcoma replicates and spreads "“ opening a door to a possible new treatment for the disease. Kaposi's Sarcoma is a cancer caused by a human herpes virus and is widespread in sub-Saharan Africa, where it is the most common cause of cancer amongst those infected with HIV. Researchers from Leeds' Faculty of Biological Sciences found that a human protein "“ known as PYM "“ is hijacked by...

2009-09-25 14:09:50

Researchers at UT Southwestern Medical Center have found that non-AIDS-defining malignancies such as anal and lung cancer have become more prevalent among HIV-infected patients than non-HIV patients since the introduction of anti-retroviral therapies in the mid-1990s. AIDS patients with suppressed immune systems are at higher risk for so-called AIDS-defining malignancies "“ cancers such as non-Hodgkin's lymphoma, Kaposi's sarcoma and cervical carcinoma. Some researchers have speculated,...

2009-09-10 16:27:00

HORSHAM, Pa., Sept. 10 /PRNewswire/ -- Centocor Ortho Biotech Products, L.P. today announced that it received a Complete Response letter from the U.S. Food and Drug Administration (FDA) regarding its Supplemental New Drug Application (sNDA) for DOXIL (doxorubicin HCI liposome injection) in combination with docetaxel for the treatment of women with locally advanced and metastatic breast cancer. Centocor Ortho Biotech is evaluating the FDA's letter and will respond to the agency as quickly...

2009-07-30 11:10:07

UCSF researchers have identified a new potential drug target for the herpes virus that causes Kaposi's sarcoma, re-opening the possibility of using the class of drugs called protease inhibitors against the full herpes family of viruses, which for 20 years has been deemed too difficult to attain.The new drug target, which is known as a protease dimer, could serve as a model for developing new therapeutics for diseases ranging from cancer to Alzheimer's, the researchers say. Findings are...

2009-07-15 16:22:00

HORSHAM, Pa., July 15 /PRNewswire/ -- Based on the data presented today, the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) recommended that the combination of DOXIL(R) (doxorubicin HCI liposome injection) and docetaxel did not provide a sufficient benefit-risk profile for the treatment of women with locally advanced or metastatic breast cancer. Women with locally advanced and metastatic breast cancer who have received prior anthracycline treatment...

2009-06-29 17:00:07

Scientists know that some cancers are triggered by viruses, which take over cellular systems and cause uncontrolled cell growth. Doctors "“ and patients who get shingles late in life "“ have also known for many years that some viruses, particularly the herpes virus, can lie dormant in a person's cells for long periods of time and then reactivate, causing disease. These viruses also cause significant disease in immunosuppressed people and those living with HIV/AIDS.A recent study...


Latest Kaposi's sarcoma Reference Libraries

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2011-02-17 15:06:48

Kaposi's sarcoma-associated herpesvirus (KSHV) one of seven currently known human cancer virus, is also the eighth human herpesvirus. Kaposi's sarcoma, caused by the virus, is common in AIDS patients, primary effusion lymphoma, and some types of multicentric Castelman's disease. Moritz Kaposi discovered the blood vessel tumor, in 1872, which would eventually be names Kaposi's sarcoma. It was originally though that KS was of Jewish and Mediterranean origins until it was found to be common...

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Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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