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Latest Kappa Opioid receptor Stories

2014-04-01 08:30:10

Rate of high risk use low among commercially insured ST. PAUL, Minn., April 1, 2014 /PRNewswire/ -- People who are at high-risk for opioid abuse use had significantly higher total medical costs ($19,513 vs. $5,493) than those who were not at high risk according to a new study by Prime Therapeutics (Prime). The Centers for Medicare & Medicare Services (CMS) defines high risk as "using a daily morphine equivalent dose (MED) of greater than 120 mg for at least 90 consecutive days,...

Scientists Solve Mystery Of How Sodium Controls Opioid Brain Signaling
2014-01-13 07:13:26

Scripps Research Institute The findings pave way for new therapies for treating pain and mood disorders Scientists have discovered how the element sodium influences the signaling of a major class of brain cell receptors, known as opioid receptors. The discovery, from The Scripps Research Institute (TSRI) and the University of North Carolina (UNC), suggests new therapeutic approaches to a host of brain-related medical conditions. "It opens the door to understanding opioid related...

2013-06-13 09:58:47

Scientists at The Scripps Research Institute (TSRI) have found evidence that an emotion-related brain region called the central amygdala–whose activity promotes feelings of malaise and unhappiness–plays a major role in sustaining cocaine addiction. In experiments with rats, the TSRI researchers found signs that cocaine-induced changes in this brain system contribute to anxiety-like behavior and other unpleasant symptoms of drug withdrawal–symptoms that typically drive an...

2013-03-07 11:22:19

In a new study in Neuron, scientists identified specific key steps in the chain of events that causes stress-related drug relapse. They identified the exact region of the brain where the events take place in rat models and showed that by blocking a step, they could prevent stress-related relapse. All too often, stress turns addiction recovery into relapse, but years of basic brain research have provided scientists with insight that might allow them develop a medicine to help. A new study...

Kicking Cocaine Addiction With A One-Two Punch
2012-08-09 10:56:41

Connie K. Ho for redOrbit.com — Your Universe Online Researchers from Scripps Research Institute recently revealed that a two-drug combination could possibly help those battling cocaine addiction. The combination made up of naltrexone and buprenoprine, two existing pharmaceutical drugs, is a therapy that would help reduce individuals´ want for cocaine and also lessen their feelings of withdrawal. Scientists believed that the therapy is a step forward as there are currently no...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.