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Last updated on April 20, 2014 at 14:04 EDT

Latest Karyotype Stories

2014-04-18 15:41:30

Researchers propose classification system revolutionizing communication of chromosomal abnormalities for research and clinical settings When talking about genetic abnormalities at the DNA level that occur when chromosomes swap, delete or add parts, there is an evolving communication gap both in the science and medical worlds, leading to inconsistencies in clinical and research reports. Now a study by researchers at Brigham and Women's Hospital (BWH) proposes a new classification system...

2013-01-10 12:23:19

REDWOOD CITY, Calif., Jan. 10, 2013 /PRNewswire/ -- Verinata Health, Inc., a privately-held company dedicated to maternal and fetal health, today announced that its proprietary prenatal technology can detect fetal subchromosomal abnormalities non-invasively from maternal blood. These proof-of-concept data show that Verinata's proprietary approach together with deep massively parallel sequencing (MPS) is able to produce a non-invasive fetal karyotype equivalent to that provided by invasive...

Chromosomal Evolution Advancement In Sea Cradles
2012-12-12 15:45:38

Pensoft Publishers The study of chromosome changes arisen during species evolution is a current and intriguing topic that evolutionary biology proposes. However, in several groups (for example, mollusks), and chitons in particular, chromosome studies are scarce, with a few species investigated and analyses performed mostly with simple methods. Only 2,5% of about 900 living species of chitons have been so far karyologically investigated, all of them in the same order (Chitonida). The...

Genetic Test Reveals More About Potential Birth Defects Than Conventional Methods
2012-12-06 11:43:12

Lawrence LeBlond for redOrbit.com - Your Universe Online Two new papers published in the New England Journal of Medicine (NEJM) show that genetic testing in early pregnancy reveals far more about potential birth defects and stillbirth risk than current prenatal testing does, based on a multi-center clinical trial using both methods. The clinical trials showed that 6 percent of certain fetuses declared normal by conventional prenatal tests were found to have genetic abnormalities using...

A Look At The Early Evolution Of Sex Chromosomes
2012-08-06 18:24:30

Two new studies offer insight into sex chromosome evolution by focusing on papaya, a multimillion dollar crop plant with a sexual problem (as far as growers are concerned) and a complicated past. The findings are described in two papers in the Proceedings of the National Academy of Sciences. The research reveals that the papaya sex chromosomes have undergone dramatic changes in their short evolutionary histories (they are about 7 million years old; by comparison, human sex chromosomes...

Does Polyploidy Play A Role In The Italian Endemic Flora?
2012-05-22 08:24:01

Besides the obvious differences between plants and animals, subtle ones lie concealed within the cell, even within the nucleus. In both plant and animal cells, the nucleus contains DNA, which condenses into chromosomes during cell division. Chromosomes can be counted at that stage, revealing the chromosome number for each species. Here comes a difference: while the chromosome number spans a relatively short range across animal species (2-296: 46 in man), some plant species have over 1000...

2012-02-23 07:00:00

REDWOOD CITY, Calif., Feb. 23, 2012 /PRNewswire/ -- Verinata Health, Inc., a privately-held company dedicated to maternal and fetal health, today published the full data from its prospective, blinded, multicenter clinical validation study to detect fetal chromosomal aneuploidies across the entire genome, including cases of fetal mosaicism and translocations. The publication, entitled "Genome-Wide Fetal Aneuploidy Detection by Maternal Plasma DNA Sequencing," was selected as Editor's Choice...

2012-02-13 09:00:00

REDWOOD CITY, Calif., Feb. 13, 2012 /PRNewswire/ -- Verinata Health, Inc., a privately-held company dedicated to maternal and fetal health, today announced the presentation of top-line results from its prospective, blinded, multicenter validation study to detect fetal chromosomal aneuploidies, or an abnormal number of chromosomes, across the entire genome. The study was specifically designed to include all samples with any abnormal karyotype in order to emulate real-world testing in which...

2012-02-10 00:07:51

While both tests look for the same thing, chromosomal microarray finds more, says New York-Presbyterian/Columbia researcher who led nationwide study A nationwide, federally funded study has found that testing a developing fetus' DNA through chromosomal microarray (CMA) provides more information about potential disorders than does the standard method of prenatal testing, which is to visually examine the chromosomes (karyotyping). The results of the 4,000-plus-participant clinical study are...

2012-01-30 08:05:57

Stress-induced genomic instability facilitates rapid cellular adaption in yeast Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions. In their latest study, researchers at the Stowers Institute for Medical Research were able to show that under stressful conditions yeast genomes become unstable, readily acquiring or...