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Latest Keratinocyte Stories

2014-05-13 16:05:05

Rockefeller University Press In addition to its known capacity to promote bleeding events, aspirin also inhibits wound healing. New research published in The Journal of Experimental Medicine now describes how aspirin acts on key skin cells called keratinocytes, delaying skin repair at wound sites. A better understanding of this process offers hope for the development of drugs to encourage wounds to heal. The public health impact of chronic wounds is significant, affecting 6.5 million...

Animal Testing Alternative - Skin Cells Grown From Human Cells
2014-04-25 03:30:51

King's College London An international team led by King's College London and the San Francisco Veteran Affairs Medical Center (SFVAMC) has developed the first lab-grown epidermis – the outermost skin layer - with a functional permeability barrier akin to real skin. The new epidermis, grown from human pluripotent stem cells, offers a cost-effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders. The...

2014-04-23 23:07:39

Stress could activate "crosstalking" cell signals that decrease the body’s natural healing process after a wound occurs, according to a new study released today in STEM CELLS Translational Medicine. The finding helps explain how stress impairs healing and, conversely, could lead to a way to overcome chronic wounds resulting from serious burns and other skin injuries. Durham, NC (PRWEB) April 23, 2014 Stress could activate "crosstalking" cell signals that decrease the...

2014-03-04 08:31:01

Groundbreaking Study Published in PLOS ONE Unveils Substantial Potential of Bioelectriceuticals in Wound Care and Beyond TEMPE, Ariz., March 4, 2014 /PRNewswire/ -- Procellera(® )- the world's first wireless microcurrent generating dressing that produces electrical fields through its matrix of microcell batteries - was found to significantly enhance cell migration in in-vitro laboratory testing, according to groundbreaking research led by The Ohio State University (OSU) Wexner...

2013-09-27 10:12:13

Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds. They found that these skin-resident immune cells function as “first responders” to skin injuries in part by producing the molecule known as interleukin-17A (IL-17A), which wards off infection and promotes wound healing. “This appears to be a critical and unique component of mammals’ defense against skin wounds, and we hope that it will...

2013-08-08 23:17:34

MD Biosciences focuses on rapid and cost effective models of psoriasis involving the IL-23/Th17 axis in order to provide companies alternatives to complex and cost prohibitive xenotransplantation models for screening. With the earlier launch of the IMQ model and now the IL-23 psoriasis model, MD Biosciences offers a range of rapid models for dermal conditions such as dermatitis and psoriasis. St Paul, MN (PRWEB) August 08, 2013 Recent psoriasis research has focused extensively on the...

2011-10-13 11:45:29

The outer layer of the skin, called the epidermis, forms a critical physical and immunological wall that serves as the body's first line of defense against potentially harmful microorganisms. Most of the epidermis consists of cells called keratinocytes that build a mechanical barrier but also perform immune functions. Now, a new study published by Cell Press in the October issue of the journal Immunity provides evidence that stopping of a type of regulated cell death called "necroptosis" in...

2009-11-20 12:40:41

Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM* Institute (I-STEM/ Inserm UEVE U861/AFM), published in the Lancet on 21 November 2009. The I-STEM team, directed by Marc Peschanski has just succeeded in recreating a whole epidermis from human embryonic stem cells. The goal is to one day be able to propose this unlimited resource of cells as an alternative treatment in particular for victims of third degree burns and patients with...

2009-10-08 14:26:30

Another role of the energy source A Japanese research group led by Prof. Makoto Tominaga and Dr. Sravan Mandadi (National Institute for Physiological Sciences: NIPS) found that ATP plays a key role in transmitting temperature information from skin keratinocytes to afferent sensory neurons. Their findings were presented in the Pflugers Archiv European Journal of Physiology published on October 2009. Hazardous temperatures (extreme hot or cold) are known to be detected by the...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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