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Latest Kevin Campbell Stories

2013-08-09 09:43:14

Study identifies 3 enzymes required for building sugar superstructure involved in muscular dystrophies For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of the disease symptoms. However, for a group of muscular dystrophies known collectively as congenital muscular dystrophies (CMDs), the sequence of the protein that is...

2012-01-09 19:10:35

Study reveals function of glycosylating enzyme involved in muscular dystrophy, brain development and infection by arenaviruses such as Lassa fever; ability to assay enzyme activity could help screen potential muscular dystrophy therapies Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 in the journal Science, could be...

2011-03-16 08:17:01

(Ivanhoe Newswire) "“ University of Iowa researchers have identified a new gene mutation that causes muscular dystrophy. In addition, by engineering the human gene mutation into a mouse, the researchers, have created a new mouse model that could help screen potential drugs to treat this type of muscular dystrophy. Normal dystroglycan, a protein that is abnormal in a group of congenital muscular dystrophies, is extensively modified with added sugar chains. This modification allows...

2011-03-10 13:33:28

Mutation in important muscle protein causes muscle disease and cognitive impairment A strong international collaboration and a single patient with mild muscle disease and severe cognitive impairment have allowed University of Iowa researchers to identify a new gene mutation that causes muscular dystrophy. Furthermore, by engineering the human gene mutation into a mouse, the researchers, led by Kevin Campbell, Ph.D., professor and head of molecular physiology and biophysics at the UI Carver...

2010-07-19 12:58:03

'Super hemoglobin' allows moles to thrive underground. Researchers writing in the open access journal BMC Evolutionary Biology have made the first identification of an adaptation in the blood of Eastern moles which allows more efficient transport of carbon dioxide, facilitating the moles' burrowing behavior. Kevin Campbell from the University of Manitoba, Canada, worked with a team of researchers to study the blood of three underground species of North American moles. He said, "Unlike...

2010-01-01 10:37:46

With the discovery of a new type of chemical modification on an important muscle protein, a University of Iowa study improves understanding of certain muscular dystrophies and could potentially lead to new treatments for the conditions. The findings, which appear in the Jan. 1, 2010, issue of the journal Science, may also have implications for detecting metastasizing cancer cells. After they are initially made, most proteins are modified through the addition of sugar chains, fats or other...

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2009-07-23 14:00:00

A new study by scientists at the University of Iowa shows why muscle membranes don't rupture when healthy people exercise.The findings shed light on a mechanism that appears to protect cells from mechanical stress. The study, which appears online July 20-24 in Proceedings of the National Academy of Sciences (PNAS) Early Edition, also helps explain why muscle damage is so severe when this mechanism is disrupted, which occurs in certain congenital and limb-girdle muscular...

2009-05-06 11:58:00

BALTIMORE, May 6 /PRNewswire-USNewswire/ -- Two scientists whose work has led to new and better ways to diagnose and potentially treat muscular dystrophy have been chosen to receive the 2009 March of Dimes Prize in Developmental Biology. Kevin P. Campbell, Ph.D. and Louis M. Kunkel, Ph.D., share the 2009 March of Dimes Prize for their pioneering work identifying the genes and proteins that cause muscular dystrophy, a disorder in which the muscles progressively degenerate. More than 250,000...

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2008-10-30 08:40:00

Feeling tired? Researchers say Viagra could help alleviate your fatigue. A team at the University of Iowa found the drug helped animals with the mislocalized enzyme called neuronal nitric oxide synthase (nNOS). They also revealed a difference between the prolonged fatigue after mild exercise in muscular dystrophy patients and the inherent muscle weakness caused by the disease. The studies found a faulty signaling pathway that leads to exercise-induced fatigue in mouse models of muscular...

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2008-02-07 16:00:00

Shrews are tiny mammals that have been widely characterized as simple and primitive. This traditional view is challenged by a new study of the hunting methods of an aquatic member of the species, the water shrew. It reveals remarkably sophisticated methods for detecting prey that allow it to catch small fish and aquatic insects as readily in the dark as in daylight. It is a skill set that the water shrew really needs. About half the size of a mouse, water shrews have such a high metabolism...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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