Latest Kinetochore Stories
Genes control everything from eye color to disease susceptibility, and inheritance - the passing of the genes from generation to generation after they have been duplicated - depends on centromeres.
Whitehead Institute scientists report that two proteins once thought to have only supporting roles, are the true "stars" of the kinetochore assembly process in human cells.
Scientists have discovered an amazingly simple way that cells stabilize their machinery for forcing apart chromosomes.
Unless you are in a field of study related to cell biology, you most likely have never heard of Ndc80.
On average, one hundred billion cells in the human body divide over the course of a day.
University of Pennsylvania biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of chromosomes during reproductive cell division.
Whitehead Institute researchers have determined a key part of how cells regulate the chromosome/microtubule interface, which is central to proper chromosomal distribution during cell division.
If you can imagine identical twin sisters at rest, their breath drawing them subtly together and apart, who somehow latch onto ropes that pull them to opposite sides of the bedâ€”you can imagine what happens to a chromosome in the dividing cell.
The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical role in the process of mitosis.
Parents of healthy newborns often remark on the miracle of life. The joining of egg and sperm to create such delightful creatures can seem dazzlingly beautiful if the chromosome information from each parent has been translated properly into the embryo and newborn.
- A bereavement by loss of parents or children; the state of being orbate; orbation.