Latest Knockout mouse Stories
In addition to fast food, desk jobs, and inertia, there is one more thing to blame for unwanted pounds-our genome, which has apparently not caught up with the fact that we no longer live in the Stone Age.
Deleting the receptor, not the protein ghrelin itself, turns up the body's fat-burning thermostat, giving aging mice an exothermic boost toward a svelte physique, researchers recently reported.
Researchers at the University of Hawai'i at MÄnoa have developed innovative techniques that could have profound effects on congenital cervical vertebrae malformation research.
Researchers at the University of Minnesota Medical School have gained insight into how different types of age-related hearing loss may occur in humans.
Elimination of a molecular gatekeeper leads to the development of arthritis in mice.
The mammalian fucose mutarotase enzyme is known to be involved in incorporating the sugar fucose into protein.
First mice, then fruit flies, and now knockout nematodes.
A quest that began over a decade ago with a chance observation has reached a milestone: the identification of a gene that may regulate regeneration in mammals.
Johns Hopkins Scientists Find a Source of Nonallergic Itch.
A Knockout Mouse is a genetically engineered mouse in which researchers have inactivated, or “knocked out,” an existing gene by replacing it or disrupting it with an artificial piece of DNA. The loss of gene activity frequently causes changes in a mouse’s phenotype, which includes appearance, behavior, or other apparent and biochemical characteristics. Knockout mice are significant animal models for studying the role of genes which have been sequenced but whose functions haven’t...
The Common House Mouse (Mus musculus), is the most numerous species of the genus Mus. It is the most common and populous mammalian species on earth, besides humans. House mice almost always live in close proximity to humans. Laboratory mice belong to strains of house mice and are some of the most important model organisms in biology and medicine. They are by far the most commonly used laboratory mammal. House mice are light brown to black, with short hair and a light belly. The ears and...
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